Fig. 4

Overview of CC’s transcriptome profile. A GO enrichment of differentially up-regulated genes in GV CC. The sizes of the points indicate the number of genes enriched in the pathway. The X-axis indicates significance. B GO results of three ontologies of CCs at the MII stage. C Differential gene expression patterns of transcripts related to amino acid metabolism and sugar metabolism in three periods. GV, blue; MI, green; MII, red. D The biological process in the GO results of the differentially highly expressed genes in the MII CC, and the Enrichment profile of these pathways. E Heat map of the expression of genes involved in de novo cholesterol synthesis at different maturation stages. F The Biological pathways of genes enriched to molecular function of CCs in the MII stage. The sizes of the points indicate the number of genes enriched in the pathway. The X-axis indicates significance. G Expression changes of key genes in fatty acid anabolism pathway at three different periods. FADS2 (Fatty Acid Desaturase 2). FABP3 (Fatty Acid Binding Protein 3). ELOVL6 (ELOVL Fatty Acid Elongase 6). ELOVL5 (ELOVL Fatty Acid Elongase 5). ACSS2 (Acyl-CoA Synthetase Short Chain Family Member 2). AACS (Acetoacetyl-CoA Synthetase). GV, blue; MI, green; MII, red