Table 3 Patient characteristics of ICSI only and IVM with ICSI patients

Age (years)

30.0 (27.0 ~ 32.0)

31.0 (28.0 ~ 35.0)

< 0.001

29 (27 ~ 31)

29 (27 ~ 31)

0.905

BMI (kg/m²)

21.6 (19.7 ~ 23.7)

21.5 (19.7 ~ 23.9)

0.931

21.0 (19.1 ~ 24.0)

21.2 (19.5 ~ 23.3)

0.745

Infertility duration(years)

3.0 (2.0 ~ 5.0)

3.0 (2.0 ~ 5.0)

0.312

3.0 (2.0 ~ 4.0)

3.0 (2.0 ~ 4.0)

0.725

Infertility type

0.005

0.366

Primary

637(73.0)

1345 (78.0)

30 (76.9)

2240 (82.5)

Secondary

236 (27.0)

380 (22.0)

9 (23.1)

476 (17.5)

Infertility causes

< 0.001

< 0.001

Female

135 (15.5)

473 (27.4)

19 (48.7)

535 (19.7)

Male

432 (49.5)

479 (27.8)

8 (20.5)

1233 (45.4)

Both

211 (24.2)

696 (40.3)

7 (17.9)

778 (28.6)

Unknown

95 (10.9)

77 (4.5)

5 (12.8)

170 (6.3)

Basal FSH (mIU/ml)

7.1 (6.2 ~ 8.2)

7.6 (6.4 ~ 8.9)

< 0.001

6.1 (5.4 ~ 7.1)

6.9 (6.0 ~ 7.9)

0.001

AFC

14 (10 ~ 20)

10.0 (7.0 ~ 15.0)

< 0.001

22.0 (15.0 ~ 24.0)

16.0 (12.0 ~ 22.0)

< 0.001

AMH (ng/ml)

4.8 (2.9 ~ 8.0)

3.0 (1.7 ~ 5.4)

< 0.001

7.5 (5.8 ~ 10.9)

6.1 (3.9 ~ 9.2)

0.002

COH protocol

< 0.001

0.765

GnRH-a

681 (78.0)

1107 (64.2)

35 (89.7)

2366 (87.1)

GnRH-ant

192 (22.0)

541 (35.8)

4 (10.3)

350 (12.9)

Gn duration(days)

10.0 (9.0 ~ 12.0)

10.0 (9.0 ~ 11.0)

< 0.001

11 (10 ~ 12)

10 (9 ~ 11)

0.051

Gn dosage(IU)

2197.5 (1650.0 ~ 2872.5)

2475.0 (1822.5 ~ 3075.0)

< 0.001

1823.0 (1275.0 ~ 2423.0)

1950.0 (1485.0 ~ 2483.0)

0.340

Follicles ≥ 14 mm on hCG day, n

12.0 (8.0 ~ 15.0)

8.0 (6.0 ~ 10.0)

< 0.001

19.0 (16.0 ~ 22.0)

14.0 (11.0 ~ 17.0)

< 0.001

Peak E2(pg/ml)

2444.0 (1690.3 ~ 3707.3)

1804.5 (1271.3 ~ 2634.5)

< 0.001

4788.0 (3000.0 ~ 5991.0)

3310 (2403.0 ~ 4925.0)

0.002

P on hCG day(ng/ml)

0.8 (0.6 ~ 1.2)

0.7 (0.5 ~ 1.0)

< 0.001

1.0 (0.7 ~ 1.6)

0.9 (0.7 ~ 1.2)

0.068

Endometrial thickness on hCG day, mm

11.7 (10.0 ~ 13.6)

11.6 (9.8 ~ 13.4)

0.211

11.8 (10.4 ~ 12.8)

12.0 (10.4 ~ 13.8)

0.336

No. of oocytes retrieved, n

13.0 (9.0 ~ 17.0)

8.0 (6.0 ~ 10.0)

< 0.001

26 (22 ~ 29)

17 (14 ~ 21)

< 0.001

No. of mature oocytes, n

Before IVM

2.0 (1.0 ~ 4.0)

6.0 (4.0 ~ 7.0)

< 0.001

10 (9 ~ 11)

13 (11 ~ 17)

< 0.001

After IVM

11.0 (8.0 ~ 14.0)

6.0 (4.0 ~ 7.0)

< 0.001

22 (21 ~ 27)

13(11 ~ 17)

< 0.001

Fertilization rate (%)

65.6

67.4

0.010

62.4

69.9

< 0.001

Blastocyst rate (%)

60.3

55.1

< 0.001

63.3

63.3

0.997

No available embryo, n

34 (3.9)

215 (12.5)

< 0.001

2 (5.1)

59 (2.2)

0.213