Investigation of androgen receptor CAG repeats length in polycystic ovary syndrome diagnosed using the new international evidence-based guideline

Table 1 The clinical features and AR CAG frequency distribution of controls and PCOS cases

Variable		Control (n = 61)	PCOS (n = 109)	p value
Baseline
Age (years)		29.52 ± 4.43	27.59 ± 4.38	0.006
BMI (kg/m²)		23.15 ± 3.57	25.32 ± 4.20	0.001
LH (IU/L)		3.57 ± 1.67	10.00 ± 6.19	< 0.001
FSH (IU/L)		5.93 ± 2.19	5.86 ± 1.66	0.837
E₂ (pg/mL)		46.69 ± 24.30	56.03 ± 37.99	0.116
TT (ng/dL)		41.76 ± 15.94	65.98 ± 34.63	< 0.001
AR CAG frequency distribution^a
Short allele	< 21	17(27.87%)	40(36.70%)	0.242
Short allele	≥ 21	44(72.13%)	69(63.30%)	-
Long allele	< 24	24(39.34%)	40(36.70%)	0.733
Long allele	≥ 24	37(60.66%)	69(63.30%)	-
Biallelic average	< 22.5	20(32.79%)	46(42.20%)	0.277
Biallelic average	≥ 22.5	41(67.21%)	63(57.80%)	-

All values were reported as mean ± SD and number (percent)
Abbreviations: PCOS polycystic ovary syndrome, BMI body mass index, LH luteinizing hormone, FSH follicle stimulating hormone, E₂ estradiol, TT total testosterone, AR androgen receptor
P value was given by the independent t-test and chi-square test
^arepresents the median CAG repeats length of all cases including controls and PCOS

ISSN: 1757-2215