Skip to main content

Table 2 Surgical parameters of 559 advanced EOC patients having cytoreductive surgery. A total of 185, 194, and 180 patients were treated during the baseline, transition, and evaluation years, respectively. Numbers are shown either as absolute numbers with percentage unless otherwise indicated

From: Prerequisites to improve surgical cytoreduction in FIGO stage III/IV epithelial ovarian cancer and subsequent clinical ramifications

Patients

Baseline Years 2014–2015

Transition Years 2016–2017

Evaluation Years 2018–2019

P-value

n = 185

n = 194

n = 180

Surgical cytoreduction

   

0.254

 PDS

49 (26.5%)

60 (30.9%)

62 (34.4%)

 

 IDS

136 (73.5%)

134 (69.1%)

118 (65.6%)

 

PCIa

Median (Range)

4 (1–8)

8 (1–24)

8 (2–21)

< 0.0001

Dissemination (GOG)b

   

0.408

 MD

17 (9.2%)

17 (8.8%)

19 (10.6%)

 

 APD

110 (59.2%)

102 (52.6%)

90 (50.0%)

 

 UAD

58 (31.3%)

75 (38.6%)

71 (39.4%)

 

Surgical Complexity Score (SCS)

   

< 0.00001

 Low (1–3)

135 (73.0%)

110 (56.7%)

74 (41.1%)

 

 Intermediate (4–7)

49 (26.5%)

68 (35.1%)

84 (46.7%)

 

 High (8–18)

1 (0.5%)

16 (8.2%)

22 (12.2%)

 

Specialist Surgeons Involvedc

   

< 0.0001

 One Gyne-Onc

164 (88.6%)

92 (47.4%)

106 (58.9%)

 

 Two Gyne-Onc’s

9 (4.9%)

72 (37.1%)

40 (22.2%)

 

 Gyne-Onc & GI

12 (6.5%)

21 (10.8%)

26 (14.5%)

 

 Gyne-Onc & HPB

 Gyne-Onc & GI & HPB

0

0

5 (2.6%)

4 (2.1%)

4 (2.2%)

4 (2.2%)

 

Residual Disease (RD)d

   

0.0041

 CC 0 (nil RD)

104 (56.2%)

127 (65.5%)

135 (75.0%)

 

 CC 1 (0 mm < RD < 2.5 mm)

33 (17.8%)

21 (10.8%)

23 (12.8%)

 

 CC 2 (2.5 mm ≤ RD < 2.5 cm)

32 (17.3%)

29 (14.9%)

17 (9.4%)

 

 CC 3 (RD ≥ 2.5 cm)

16 (8.7%)

17 (8.8%)

5 (2.8%)

 

Blood Loss (mL)

Mean ± SD

469 ± 321

549 ± 362

551 ± 464

0.109

  1. a PCI represents peritoneal cancer index as published previously [23]
  2. b MD (minimal disease), APD (abdominal peritoneal disease), AUD (upper abdominal disease) according to GOG criteria [24]
  3. c Gyne-Onc, GI, and HPB represent Gynecologic Oncologist, Gastro-Intestinal Specialist Surgeon, and Hepato-Billiary Specialist Surgeon, respectively
  4. d CC represents completeness of cytoreduction according to Sugarbaker criteria as published previously [21]