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Table 3 Postoperative parameters of 559 advanced EOC patients having cytoreductive surgery. A total of 185, 194, and 180 patients were treated during the baseline, transition, and evaluation years, respectively. Numbers are shown either as absolute numbers with percentage unless otherwise indicated

From: Prerequisites to improve surgical cytoreduction in FIGO stage III/IV epithelial ovarian cancer and subsequent clinical ramifications

Patients

Baseline Years 2014–2015

Transition Years 2016–2017

Evaluation Years 2018–2019

P-value

n = 185

n = 194

n = 180

Postoperative Admissions

   

< 0.0001

 Regular Ward Admission

170 (91.9%)

138 (71.1%)

124 (68.9%)

 

 Pre-planned HDU/ITU Admission

1 (0.5%)

19 (9.8%)

32 (17.8%)

 

 Planned HDU/ITU Admission

7 (3.8%)

33 (17.0%)

20 (11.1%)

 

 Unplanned HDU/ITU Admission

7 (3.8%)

4 (2.1%)

4 (2.2%)

 

Hospital Stay (days)

Mean ± SD

7.0 ± 2.6

8.3 ± 4.9

8.4 ± 4.9

0.0014

Chemotherapy Regimena

   

0.449

 No Adjuvant CT

18 (9.7%)

27 (13.9%)

21 (11.7%)

 

 Adjuvant CT

167 (90.3%)

167 (86.1%)

159 (88.3%)

 

Planned Adjuvant CTb

   

0.811

 Started ≤ 6w after surgery

157 (94.0%)

154 (92.2%)

148 (93.1%)

 

 Started > 6w after surgery

10 (6.0%)

13 (7.8%)

11 (6.9%)

 

Peri-operative Morbidity

   

0.142

 Clavien-Dindo Grade 0–2

167 (90.3%)

180 (92.8%)

156 (86.7%)

 

 Clavien-Dindo Grade ≥ 3 A

18 (9.7%)

14 (7.2%)

24 (13.3%)

 

Postoperative Mortality

   

0.635

 Alive after 60-days

182 (98.4%)

193 (99.5%)

179 (99.4%)

 

 Death < 30-days

1 (0.5%)

0 (0.0%)

0 (0.0%)

 

 30-days ≤ Death < 60-days

2 (1.1%)

1 (0.5%)

1 (0.6%)

 
  1. a CT represents chemotherapy
  2. b The number of patients who were planned to have adjuvant chemotherapy equaled 167, 167, and 159 during the baseline, transition, and evaluation years, respectively