Fig. 1
p53 status does not influence cell migration or invasion, but does influence mevalonate pathway expression in OVE cells. A OVE cells were seeded and incubated for 24 h in transwell chambers (n = 3/group) then stained with toluidine blue and the percent area invaded was calculated. B Protein was collected from OVE cells (n = 4/group) and western blotting was performed for mevalonate pathway members. Bars represent mean ± SEM (*p < 0.05, **p < 0.01, ***p < 0.001). Scale bars: 500 μm. Abbreviations: WT wild-type; MUT p53R175H mutant; KO Trp53 knockout