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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: The effect of paclitaxel- and fisetin-loaded PBM nanoparticles on apoptosis and reversal of drug resistance gene ABCG2 in ovarian cancer

Fig. 3

PBM NP-mediated apoptosis in OvCa cells. Flow cytometric analysis of Annexin V-FITC- and PI-stained OvCa cells treated with FA-PBM NPs, [A] OVCAR3 cells, and [B] CAOV3 cells treated with IC50 concentrations of Fis-FA and PTX-FA NPs, alone and in combination for 48 h. The numbers in each quadrant indicate the percentage of Q1 (necrotic): Annexin (-)/(PI (+), Q2 (late apoptotic): (Annexin (+)/(PI(+), Q3 (viable): Annexin (-)/(PI(-), and Q4 (early apoptotic): Annexin (+)/(PI (-) cells. Data were analyzed by FlowJo software version 10

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