Fig. 4

Combined FA PBM NPs modulate the expression of apoptotic markers in OvCa cells. Expression of pro-apoptotic (BAK), apoptotic (active caspase-3), and anti-apoptotic (BCL-XL) proteins in [A] OVCAR3 and [B] CAOV3 cells treated with Fis and PTX NPs, alone and in combination, for 48 h. An internal standard for equal loading, blots were probed with a GAPDH antibody. BAK, Caspase-3, and BCL-XL band intensity were normalized against GAPDH, and their densitometry are shown below