Fig. 5

The effect of UBE2S gene knockdown on the proliferation of platinum-resistant ovarian cancer cells. A Statistical analysis of CCK8 test results of SKOV3/DDP and A2780/DDP cell lines. The blue line represents the control group, and the yellow line represents the UBE2S gene knockdown group. The cell proliferation rate was measured at 0 h, 24 h, 48 h and 72 h. B Ki-67 immunofluorescence staining of the control group and UBE2S gene knockdown group in SKOV3/DDP and A2780/DDP cell lines. Red is Ki-67 staining, blue is DAPI nuclear staining, and Merge merges the image. The histogram counts the number of Ki-67 cells. C Experimental results and statistics of cell colony formation after SKOV3/DDP and A2780/DDP cell line transfection. *p < 0.05, **p < 0.01, ***p < 0.001