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Fig. 7 | Journal of Ovarian Research

Fig. 7

From: Activation of PI3K/AKT/mTOR signaling axis by UBE2S inhibits autophagy leading to cisplatin resistance in ovarian cancer

Fig. 7

The relationship between UBE2S gene knockout and autophagy in cisplatin-resistant ovarian cancer. A MDC-stained confocal micrographs of autophagy induced by knockdown of UBE2S in SKOV3/DDP cells. B MDC-stained confocal micrographs of autophagy induced by knockdown of UBE2S in A2780/DDP cells. MDC immunofluorescence staining of sh-NC and sh-UBE2S-treated cells for 24 h. Green is MDC-stained autophagosomes. C GFP-LC3-B adenovirus immunofluorescence marker staining in SKOV3/DDP cell lines in sh-NC and sh-UBE2S-treated groups. D GFP-LC3-B adenovirus immunofluorescence marker staining in A2780/DDP cell lines in sh-NC and sh-UBE2S-treated groups. * p < 0.05, ** p < 0.01, *** p < 0.001

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Journal of Ovarian Research

ISSN: 1757-2215

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