Table 1 Demography and clinical characteristics of eight patients with synchronous primary endometrial and ovarian neoplasm
NO | Age | Complaint | Hyperlipemia | Type2 Diabetes | IR | MS | Family history of cancers | Lynch screening | Germline mutation testing | CA125 (U/mL) | HE4 (pmol/L) | Pathology of endometrium | Immunohistochemistry of endometrial lesions | Pathology of ovarian tumors | Originated from endometrioid cysts | FIGO staging of ovarian tumor |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case1 | 32 | AUB, adnexal mass | NO | NO | NO | NO | YES | Negative | No data | 21 | 94.4 | EEA, G1 | ER(+ ,60%),PR(+ ,10%),Ki-67(+ ,1%),P53(+ , wild type) | Endometrioid carcinoma | YES | IA |
Case2 | 28 | AUB | NO | NO | NO | NO | NO | Negative | No data | 17.7 | 38.5 | EEA, G1 | ER(+ ,80%),PR(+ ,10%),Ki-67(+ ,8%),P53(+ ,wild type) | Endometrioid carcinoma | NO | IA |
Case3 | 34 | AUB, adnexal mass | YES | YES | YES | YES | YES | Negative | Negative | 65 | 147 | EEA, G1 | ER(+ ,80%), PR(+ ,80%), Ki-67(+ ,10%),P53(+ ,wild type) | Endometrioid carcinoma with local dedifferentiated carcinoma | YES | IA |
Case4 | 34 | abdominal pain and adnexal mass | NO | NO | NO | NO | NO | Negative | Negative | 62 | 195 | EEA, G1 | ER(+ ,80%),PR(+ , 80%),Ki-67(+ ,40%),P53(+ ,wild type) | Endometrioid carcinoma | NO | IC1 |
Case5 | 29 | AUB, adnexal mass | NO | NO | NO | NO | YES | Negative | No data | 24 | 35.7 | EEA, G1 | ER(+ ,70%), PR(+ ,80%), Ki-67(+ ,20%),P53(+ ,wild type) | Endometrioid borderline tumor | YES | IC1 |
Case6 | 30 | abdominal pain and adnexal mass | NO | NO | NO | NO | NO | Negative | Negative | 15.97 | 41.7 | EEA, G1 | ER( +),PR( +),Ki67(+ ,5%),p53(+ ,wild type) | Endometrioid borderline cystadenoma | YES | IA |
Case7 | 28 | AUB | NO | NO | NO | NO | YES | Negative | Negative | 23.6 | 35.7 | EAH | ER(+ ,95%),PR(+ ,60%),Ki-67(15% + ,P53(+ ,wild type) | Serous borderline tumor | NO | IC |
Case8 | 31 | AUB, adnexal mass | NO | NO | NO | NO | YES | Negative | No data | 18 | 41.5 | EAH | ER(+ ,90%),PR(+ ,90%),Ki67(+ ,30%),P53(+ ,wild type) | Endometrioid borderline cystadenoma | YES | I |