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Fig. 12 | Journal of Ovarian Research

Fig. 12

From: Administration of adipose-derived mesenchymal stem cell conditioned medium improves ovarian function in polycystic ovary syndrome rats: involvement of epigenetic modifiers system

Fig. 12

The effects of ASC and ASC-CM transplantation on 5mC (A,A´) and 5hmC (B,B´) nuclear protein levels 4 weeks after treatment in the left ovary of PCOS rat model. Values represent the means ± SEM from each group. One-way ANOVA followed by Tukey’s post hoc test was used to analyze data. Positive cells (brown staining) were detected in both the parenchymal and luteal structures of the ovaries. *shows significant differences vs Sham (*P ≤ 0.05). #shows significant differences vs CTRL group (.#P ≤ 0.05). Abbreviations: CTRL, Control group; ASC, Adipose stem cell group; ASC-CM, Adipose stem cell-conditioned media group; 5mC, 5methyl-cytosine; 5hmC, 5-Hydroxymethylcytosine; SEM, standard error of the mean. Magnification and Scale bars =  × 100; 100 µm (a–d) and × 200; 50 µm (e–h)

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Journal of Ovarian Research

ISSN: 1757-2215

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