Table 4 Clinical and live birth outcomes of single euploid and mosaic embryo transfers in young and advanced age groups
|  | Total ages | < 38 years | ≥ 38 years | |||
|---|---|---|---|---|---|---|
Euploid embryos (N = 1301) | Mosaic embryos (N = 60) | Euploid embryos (N = 1008) | Mosaic embryos (N = 45) | Euploid embryos (N = 293) | Mosaic embryos (N = 15) | |
PGT indication | ||||||
 No. of patients undergoing PGT-A | 805 (61.88%) | 37 (61.67%) | 546 (54.17%) | 23 (51.11%) | 259 (88.40%) | 14 (93.33%) |
 No. of patients undergoing PGT-SR | 496 (38.12%) | 23 (38.33%) | 462 (45.83%) | 22 (48.89%) | 34 (11.60%) | 1 (6.67%) |
Antral ovarian follicle count | 15.00 (10.00, 21.00) | 14.00 (9.00, 21.00) | 15.00 (10.00, 21.00) | 16.00 (9.00, 21.00) | 12.00 (8.00, 18.00) | 12.00 (7.50, 18.00) |
Female age at controlled ovarian stimulation (year) | 33.00 (30.00, 36.00) | 33.00 (31.00, 36.25) | 32.00 (29.00, 34.00) | 32.00 (31.00, 34.00) | 39.00 (38.00, 40.00) | 40.00 (38.50, 40.00) |
Female age at transfer cycle (year) | 34.00 (31.00, 37.00) | 34.00 (32.00, 37.25) | 32.00 (30.00, 34.00) | 32.00 (31.00, 35.00) | 39.00 (39.00, 41.00) | 40.00 (39.00, 41.50) |
No. of transfer cycles | 1.00 (1.00, 2.00) | 2.00 (1.00, 2.00) | 1.00 (1.00, 2.00) | 2.00 (1.00, 2.00) | 1.00 (1.00, 3.00) | 2.00 (1.00, 2.00) |
Endometrial thickness at transfer (mm) | 8.00 (7.00, 10.00) | 8.00 (7.00, 10.00) | 9.00 (8.00, 10.00) | 8.00 (8.00, 10.00) | 8.00 (7.00, 9.00) | 8.00 (6.50, 9.00) |
Implantation rate (%,no./total no.) | 68.49% (891/1301) | 58.33% (35/60) | 70.24% (708/1008) | 66.67% (30/45) | 62.46% (183/293)a | 33.33% (5/15)a |
Clinical pregnancy (%,no./total no.) | 57.65% (750/1301)b | 41.67% (25/60)b | 59.92% (604/1008) | 46.67% (21/45) | 49.83% (146/293) | 26.67% (4/15) |
Miscarriage rate (%,no./implantation no.) | 9.20% (82/891) | 2.86% (1/35) | 8.76% (62/708) | 3.34% (1/30) | 10.93% (20/183) | 0% (0/5) |
Ectopic pregnancy rate (%,no./clinical pregnancy no.) | 0c | 4.00% (1/25)c | 0 | 4.76% (1/21) | 0 | 0% (0/4) |
Live birth rate (%,no./total no.) | 51.35% (668/1301)d | 38.33% (23/60)d | 53.77% (542/1008) | 42.22% (19/45) | 43.00% (126/293) | 26.67% (4/15) |
Gestational age at delivery (week) | 38.66 ± 1.82 | 38.83 ± 1.07 | 38.74 ± 1.85 | 38.88 ± 1.15 | 38.31 ± 1.68 | 38.81 ± 0.60 |
Birth weight (g) | 3286.07 ± 520.90 | 3206.96 ± 443.01 | 3315.29 ± 526.61 | 3167.37 ± 471.53 | 3155.36 ± 532.67 | 3395.00 ± 219.32 |
Congenital anomaly rate (%,no./total no.) | 0 | 4.35% (1/23) | 0 | 5.26% (1/19) | 0 | 0 |