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Table 2 Transcription factor binding sites identified within the GSN promoter sequence region (prediction and visualization using match 1.0 weight-based matrix program from TRASNFAC 6.0. (http://gene-regulation.com/pub/programs.html#match)

From: The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

Name

Sequence

Position

(0-based)

Strand

Score

p-value

E-value

STAT3

(M00497)

GGGTTCCC

179

-

7.35

0.00045

0.188

Msx-1

(M00394)

CACTAAATG

70

-

8.71

5.0E-5

0.0208

CREB

(M00177)

CCTGACATACGG

98

-

9.05

0.000575

0.237

Oct-1

(M00162)

AGGCCTGACATACG

99

-

8.73

0.000975

0.40

YY1

(M00059)

TGCGCCCATTTAGTGTG

64

+

9.47

0.00015

0.061

  1. STAT3, Signal transducer and activator of transcription; MSX-1, Msh homeobox 1, CREB, cAMP response element-binding protein; OCT-1, octamer-binding protein