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Table 1 General information of patients

From: Exosomal biomarkers in the differential diagnosis of ovarian tumors: the emerging roles of CA125, HE4, and C5a

Item

Totaldata

Pathology

T

P

Benign group

Non-benign group

Age

36.162 ± 11.749

34.784 ± 11.348

42.910 ± 10.929

4.441

< 0.0001

Serum

CA125(U/mL)

80.322 ± 138.873

46.231 ± 68.991

260.343 ± 249.626

4.968

< 0.0001

HE4(pmol/L)

79.633 ± 144.756

50.235 ± 12.287

248.770 ± 335.300

3.452

< 0.0001

Serum sEVs

OCS

0.306 ± 0.259

0.229 ± 0.179

0.640 ± 0.286

9.125

< 0.0001

CA125(U/mL)

26.037 ± 62.415

9.226 ± 21.238

98.629 ± 111.739

5.285

< 0.0001

HE4(pmol/L)

3.473 ± 9.190

1.900 ± 0.751

10.269 ± 19.925

2.786

< 0.0001

C5a(ng/ml)

4.902 ± 2.572

4.454 ± 2.188

6.837 ± 3.178

4.720

< 0.0001

ROMA idex

14.600 ± 19.523

9.064 ± 6.043

44.520 ± 36.839

5.594

< 0.0001