Table 3 Comparison of CA125 and HE4 levels in serum sEV and serum pairs

Total data

S-CA125&E-CA125

0.805

54.286

96.079

8.643

< 0.001

S-HE4&E-HE4

0.752

76.160

137.981

8.443

< 0.001

Benign group

S-CA125&E-CA125

0.697

37.01

56.29

9.061

< 0.001

S-HE4&E-HE4

0.281

48.34

12.10

55.076

< 0.001

Non-benign group

S-CA125&E-CA125

0.749

128.91

170.51

5.015

< 0.001

S-HE4&E-HE4

0.713

196.31

290.39

4.484

< 0.001