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Table 6 Comparison of the AUC of each index for the diagnosis of ovarian tumours

From: Exosomal biomarkers in the differential diagnosis of ovarian tumors: the emerging roles of CA125, HE4, and C5a

 

Serum

Serum sEVs

ROMA

CA125(U/mL)

HE4(pmol/L)

OCS

CA125(U/mL)

HE4(pmol/L)

C5a(ng/ml)

Serum

CA125(U/mL)

-

0.1506

0.0067

0.0034

0.1421

0.6932

0.2154

HE4(pmol/L)

0.1506

-

0.1421

0.5097

0.9699

0.2056

0.9523

Exosome

OCS

0.0067

0.1421

-

0.1569

0.0409

0.0009

0.1668

CA125(U/mL)

0.0034

0.5097

0.1569

-

0.6077

0.0371

0.5136

HE4(pmol/L)

0.1421

0.9699

0.0409

0.6077

-

0.1149

0.9396

C5a(ng/ml)

0.6932

0.2056

0.0009

0.0371

0.1149

-

0.2306

ROMA

0.2154

0.9523

0.1668

0.5136

0.9396

0.2306

-