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Table 5 Significant metabolic pathways involved in different OC phenotypes

From: Exploring the causal role of multiple metabolites on ovarian cancer: a two sample Mendelian randomization study

Traits

Metabolic pathways

Total

Hits

Expected

P-value

MOC

Caffeine metabolism

10

2

0.019

0.019

MOC

Arginine biosynthesis

14

1

0.027

0.027

MOC

Citrate cycle (TCA cycle)

20

1

0.039

0.038

OCED

Caffeine metabolism

10

1

0.039

0.038

OCED

alpha-Linolenic acid metabolism

13

1

0.050

0.049

  1. Abbreviations: OC Ovarian cancer, OCED Endometrioid ovarian cancer, OCCC Clear cell ovarian cancer SOC Serous ovarian cancer, MOC Mucinous ovarian cancer
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Journal of Ovarian Research

ISSN: 1757-2215

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