Fig. 2
From: Loss of Calponin 2 causes premature ovarian insufficiency in mice
Cnn2 −/− female mice exhibited age-progressive decline in reproductive litter size. The scattered plots demonstrate a significant negative correlation of the litter size with maternal age of Cnn2-KO female breeders (from mating at 1–9 months old) (p = 0.006 two-tail Pearson’s correlation analysis). The litter size of age-matched WT mothers remained stable during this age period (p = 0.349)