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Table 2 Comparison of baseline acne score acne global score and laboratory investigations at baseline and after treatment

From: The impact of oral isotretinoin on ovarian functions of acne patients complaining of polycystic ovarian syndrome: a prospective study

 

Baseline (n= 40)

After treatment (n= 40)

95% CI

P

M F-G Score

11.02 ± 3.02

10.16 ± 2.32

0.19. 0.17

*<0.01

Acne score

2.42 ± 0.844

0.73 ± 0.452

1.4, 2.0

*<0.001

The global score

11.58 ± 5.857

1.65 ± 1.369

8.0, 11.8

*<0.001

FSH

7.00 ± 0.558

7.00 ± 0.593

-0.07, 0.07

0.959

LH

5.43 ± 1.126

5.36 ± 1.127

-0.06, 0.18

0.294

E2

48.43 ± 8.755

48.72 ± 9.045

-0.80, 0.23

0.270

DHEAS

216.35 ± 29.834

214.17 ± 31.406

-0.08, 4.45

0.058

TT

0.47 ± 0.062

0.47 ± 0.061

0.00, 0.01

0.377

FT

1.82 ± 0.286

1.56 ± 0.253

0.21, 0.30

*<0.001

AST

23.72 ± 3.093

23.77 ± 3.287

-0.30, 0.20

0.678

ALT

22.40 ± 1.930

22.33 ± 1.984

-0.16, 0.29

0.552

Cholesterol

138.08 ± 15.029

160.32 ± 20.002

-25.08, -19.39

*<0.001

TG

119.38 ± 7.500

138.79 ± 11.474

-21.89, -16.93

*<0.001

  1. MF-G Modified Ferriman-Gallwey Score; FSH: follicle stimulating hormone, LH: luteinizing hormone, E2: estradiol, DHEAS: dehydroepiandrosterone sulfate, TT: testosterone, FT: free testosterone, AST: alanine transaminase, AST: aspartate transaminase, TG: triglycerides, CI confidence level of 95%, p: probability, *statistically significant if p < 0.05