Fig. 3

Effect of Paqr7-knockout on female fertility. (A, B) The fertility of Paqr7^−/− female mice was evaluated by being caged with for 6 months and the offsprings were observed and counted regularly. Effects of the Paqr7 knockout on female fertility. The mating was performed as follows: Wild-type (Paqr7^+/+) and Paqr7^−/− female mice were mated with male mice of known fecundity (one male mouse and one female mouse in each cage and seven cages for each group). The litters (A) and litter sizes (B) were recorded for about six months. (C) Statistics on the number of oocytes in the natural ovulation experiment in wild-type female mice (n = 3) and Paqr7^−/− female mice (n = 3). Values are presented as the mean ± SD, **P < 0.01, ***P < 0.001, compared with Paqr7^+/+ mice by the student t-test