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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Progestin and adipoQ receptor 7 (PAQR7) mediate the anti-apoptotic effect of P4 on human granulosa cells and its deficiency reduces ovarian function in female mice

Fig. 4

Effect of Paqr7-knockout on ovarian weight, microstructure and follicle development. (A, B) Effects of the Paqr7 knockout on the weight of ovary and the ovary index. (C) The morphologies of ovaries in 2-month-old wildtype (Paqr7+/+) and Paqr7-knockout (Paqr7−/−) female mice were examined after haematoxylin-eosin (HE) staining. (D-H) Statistical analyses of different stages of follicles in 3-month-old Paqr7+/+ (n = 3) and Paqr7−/− female mice (n = 3) were performed according to the HE staining results. The primary follicles (PF) containing one to two layers of cuboidal granulosa cells, enlarged oocytes, and measuring between 30 and 70 μm in diameter, and final follicle growth and maturation were evaluated by counting the number of mid- and large-antral follicles (ANF), measuring from 250 to > 400 μm. *P < 0.05, compared with Paqr7+/+ mice by the student t-test

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Journal of Ovarian Research

ISSN: 1757-2215

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