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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Progestin and adipoQ receptor 7 (PAQR7) mediate the anti-apoptotic effect of P4 on human granulosa cells and its deficiency reduces ovarian function in female mice

Fig. 5

Effect of Paqr7 knockout on reproductive endocrine function in female mice. (A) Analysis of the estrous cycle by smear of exudated cells from the mouse vagina. (B) Effects of estrous cycle regularity in Paqr7−/− compared with Paqr7+/+ female mice. n = 7, values are presented as the mean ± SEM. ***P < 0.001, compared with Paqr7+/+ mice by the Student t-test. (C-F) The concentrations of serum anti-müllerian hormone (AMH, C), estradiol (E2, D), follicle-stimulating hormone (FSH, E), and progesterone (P4, F) in 2-month-old Paqr7+/+ (n = 3) and Paqr7−/− (n = 3) female mice were examined by enzyme-linked immunosorbent assay. Values are presented as the mean ± SEM. *P < 0.05, **P < 0.01, compared with PAQR7+/+ mice by the student t-test

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Journal of Ovarian Research

ISSN: 1757-2215

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