Skip to main content

Table 1 Characteristics of study participants

From: Maternal and perinatal risks for monozygotic twins conceived following frozen-thawed embryo transfer: a retrospective cohort study

Characteristics

DZT (N = 6101)

MZT (N = 164)

P value

Maternal age of delivery, mean (SD), y

31.8 (3.69)

32.5 (4.13)

0.061

Maternal age of oocyte retrieval, mean (SD), y

30.6 (3.64)

31.1 (4.07)

0.121

Duration of infertility, mean (SD), y

3.04 (2.48)

3.43 (2.65)

0.067

Gravidity

  

0.591

 0

3527 (57.8%)

89 (54.3%)

 

 1

1408 (23.1%)

39 (23.8%)

 

 ≥2

1166 (19.1%)

36 (22.0%)

 

Primiparous status

5661 (92.8%)

151 (92.1%)

0.845

Pregestational BMI, kg/m2

  

0.006

 <18.5

646 (10.6%)

31 (18.9%)

 

 18.5–24

4193 (68.7%)

102 (62.2%)

 

 24–28

959 (15.7%)

21 (12.8%)

 

 >28

235 (3.85%)

8 (4.88%)

 

Number of oocytes retrieved

13.2 (7.91)

13.1 (8.68)

0.881

Fertilization method

  

0.249

 IVF

3778 (61.9%)

107 (65.2%)

 

 ICSI

1533 (25.1%)

43 (26.2%)

 

 IVF + ICSI

790 (12.9%)

14 (8.54%)

 

FET cycle rank

  

0.524

 1–3

5746 (94.2%)

152 (92.7%)

 

 4–11

355 (5.82%)

12 (7.32%)

 

FET protocol

  

0.897

 Natural

1296 (21.2%)

36 (22.0%)

 

 HRT

2036 (33.4%)

52 (31.7%)

 

 OI

2756 (45.2%)

76 (46.3%)

 

Stage of embryos transferred

  

< 0.001

 D2-3

5351 (87.7%)

119 (72.6%)

 

 D5-6

728 (11.9%)

44 (26.8%)

 

 Cleavage-stage embryo + blastocyst

22 (0.36%)

1 (0.61%)

 

Number of embryos transferred

  

< 0.001

 1

0 (0.00%)

38 (23.2%)

 

 2

6063 (99.4%)

125 (76.2%)

 

 3

38 (0.62%)

1 (0.61%)

 

Year of treatment

0 (0.00%)

38 (23.2%)

< 0.001

 2007–2011

214 (3.51%)

16 (9.76%)

 

 2012–2016

3403 (55.8%)

87 (53.0%)

 

 2017–2021

2484 (40.7%)

61 (37.2%)

 
  1. BMI, body mass index; DZT, dizygotic twins; FET, frozen embryo transfer; ICSI, intracytoplasmic sperm injection; IVF, in vitro fertilization; MZT, monozygotic twins; SD, standard deviation