Table 2 Analysis of odds ratios of neonatal risks in monozygotic twins compared to dizygotic twins
Neonatal outcomes | DZT (N = 6101) | MZT (N = 164) | cOR (95% CI) | aOR (95% CI)a | aOR (95% CI)b |
|---|---|---|---|---|---|
Neonatal death | 49 (0.80%) | 4 (2.47%) | 3.12 (0.94–7.78) | 4.19 (1.23–10.8) | 4.95 (1.41–13.2) |
Preterm birth, < 37 weeks | 3043 (50.3%) | 119 (75.3%) | 3.01 (2.11–4.39) | 2.55 (1.72–3.89) | 2.31 (1.48–3.67) |
Very preterm birth, < 32 weeks | 241 (3.99%) | 5 (3.16%) | 0.79 (0.28–1.74) | 0.85 (0.26–2.05) | 0.87 (0.26–2.22) |
Extremely preterm birth, < 28 weeks | 40 (0.66%) | 1 (0.63%) | 0.96 (0.05–4.44) | 1.38 (0.08–6.56) | 1.80 (0.09-10.0) |
Low birth weight, < 2500 g | 3267 (54.0%) | 111 (70.3%) | 2.01 (1.43–2.86) | 2.08 (1.41–3.14) | 1.92 (1.27–2.93) |
Very low birth weight, < 1500 g | 216 (3.57%) | 7 (4.43%) | 1.25 (0.53–2.51) | 1.23 (0.43–2.77) | 1.20 (0.41–2.79) |
Small for gestational age | 376 (6.22%) | 19 (12.0%) | 2.06 (1.22–3.28) | 2.20 (1.23–3.70) | 2.18 (1.21–3.69) |
Large for gestational age | 1139 (18.8%) | 19 (12.0%) | 0.59 (0.35–0.93) | 0.53 (0.28–0.91) | 0.55 (0.29–0.95) |
Macrosomia, > 4000 g | 7 (0.12%) | 0 (0.00%) | NA | NA | NA |
Birth weight discordance | 783 (12.9%) | 15 (9.49%) | 0.71 (0.40–1.17) | 0.59 (0.29–1.08) | 0.57 (0.28–1.04) |
Stillbirth | 5 (0.08%) | 2 (1.22%) | 15.1 (2.14–70.4) | 10.7 (0.53–76.5) | 12.0 (0.55–99.4) |
Birth defects | 188 (3.08%) | 5 (3.09%) | 1.00 (0.35–2.22) | 1.52 (0.53–3.43) | 1.39 (0.48–3.17) |
Neonatal jaundice | 115 (1.90%) | 4 (2.53%) | 1.34 (0.41–3.24) | 1.96 (0.59–4.84) | 1.92 (0.58–4.77) |
Pneumonia | 53 (0.88%) | 2 (1.27%) | 1.45 (0.24–4.72) | 2.25 (0.36–7.51) | 2.47 (0.39–8.32) |
Respiratory distress syndrome | 20 (0.33%) | 0 (0.00%) | NA | NA | NA |
Necrotizing enterocolitis | 7 (0.12%) | 0 (0.00%) | NA | NA | NA |