Table 1 Baseline characteristics of the patients

Case

1

2

3

4

5

6

7

8

9

10

Year

2015

2017

2018

2019

2020

2021

Diagnosis

HL^c

Ovarian tumor (Germ cell)

HL

HL

Ewing Sarcoma

Ovarian tumor (Dysgerminoma)

HL

Brain tumor (Medulloblastoma)

Osteogenic tumor

HL

Age (year)

16

16

17

17

16

15

17

16

14

17

Menarche age

12

13

N/A

11

10

13

14

12

13

11

BMI (kg/m²)

19.1

19.9

18.1

20.3

19.2

19.5

19.6

19.1

24.9

19.1

Ovarian surgery^a

Cryopreservation of ½ left ovarian tissue^d

Right Oophorectomy

No

No

No

Right Oophorectomy

No

No

No

No

Radiotherapy^b

No

No

No

No

No

No

No

No

No

No

Chemotherapy^b

No

No

No

No

No

No

No

No

No

No

Menstruation

Regular

Irregular

Irregular

Irregular

Regular

Irregular

Regular

Irregular

Irregular

Regular

AFC

4

6

16

14

16

6

14

20

20

20

AMH (ng/ml)

N/A^e

0.4

0.9

0.9

5.1

1.9

N/A

8.9

N/A

6.0

FSH (IU/L)

3.7

4.2

9.1

9.1

3.4

6.7

4.5

3.9

9.0

2.2

LH (IU/L)

9.4

8.8

7.8

5.3

2.6

12.4

3.2

0.6

12.5

5.0

Prog (ng/ml)

0.2

2.5

0.2

1.1

N/A

0.5

N/A

0.2

0.2

1.2

E2 (pg/ml)

88.3

141.9

40.3

188.0

N/A

33.2

N/A

17.5

144

N/A