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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Bushenhuoluo Decoction improves polycystic ovary syndrome by regulating exosomal miR-30a-5p/ SOCS3/mTOR/NLRP3 signaling-mediated autophagy and pyroptosis

Fig. 5

BSHLD attenuated LPS-triggered pyroptosis in GCs by decreasing exosomal miR-30a-5p. A ELISA analysis of IL-1β and IL-18 levels in the supernatant of GCs. B The pyroptosis of GCs was determined by flow cytometry. C RT-qPCR analysis of NLRP3, ASC, and Caspase 1 mRNA levels in GCs. D The protein abundance of NLRP3 was detected by Western blotting. Results are presented as mean ± SD. n = 3. * p < 0.05, ** p < 0.01, *** p < 0.001

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