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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer

Fig. 5

SETDB1 promotes the expression of SF3B4 in ovarian cancer. A Cistrome DB data showed the binding peak of SETDB1 protein in the SF3B4 promoter region. B Visualization analysis of Cistrome project 2124 data by IGV showed the SETDB1 binding site in SF3B4 promoter. C TCGA-OV database showed the positive correlation between SETDB1 and SF3B4 mRNA expression in ovarian cancer. D, E qRT-PCR and WB showed the effect of SETDB1 knockdown on SF3B4 mRNA and protein expression in ovarian cancer. F Luciferase reporter assays showed the effect of SETDB1 on SF3B4 promoter in HEY cells

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