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Table 1 Demographic data and baseline characteristics of patients

From: Metformin versus metformin plus pioglitazone on gonadal and metabolic profiles in normal-weight women with polycystic ovary syndrome: a single-center, open-labeled prospective randomized controlled trial

 

PIOMET (N = 18)

MET (N = 18)

P value

Age (years)

25.33 ± 5.45

23.94 ± 5.29

0.4428

Height (m)

1.64 ± 0.05

1.64 ± 0.06

0.9138

Body weight (kg)

57.22 ± 6.24

58.69 ± 6.72

0.5001

BMI (kg/m2)

21.63 (19.99–23.37)

23.32 (19.84–23.84)

0.3040

AMH (ng/mL)

13.53 ± 5.54

10.25 ± 6.13

0.1013

LH (mIU/mL)

16.45 (13.15–22.26)

15.26 (11.81–22.31)

0.5841

FSH (mIU/mL)

7.02 ± 1.87

7.28 ± 2.39

0.7279

LH/FSH

2.83 ± 1.41

2.57 ± 1.34

0.5791

TT (ng/mL)

0.74 (0.59–0.92)

0.79 (0.63–0.99)

0.5572

FAI (%)

6.45 (4.37–10.56)

13.62 (7.07–18.62)

0.0616

SHBG (nmol/L)

41.25 (30.55–54.20)

26.10 (14.73–38.35)

0.1038

AND (ng/mL)

4.21 ± 1.68

3.96 ± 2.34

0.7532

DHEAS (ng/mL)

276.80 ± 103.80

260.80 ± 84.56

0.6661

FPG (mmol/L)

5.21 (4.99–5.57)

5.31 (4.79–5.44)

0.7260

FINS (mU/L)

6.90 (5.75–11.85)

10.05 (5.60–13.50)

0.5960

HOMA-IR

1.79 (1.31–2.71)

2.46 (1.29–3.15)

0.4828

AUCIns (mU/L*min)

6615 (4853–11,156)

10,872 (6875–17,778)

0.1061

AUCGlu (mmol/L*min)

1162 (930.5–1371)

1213 (997.8–1335)

0.7084

AUCIns/AUCGlu

6.99 ± 3.91

11.13 ± 7.78

0.0584

  1. PIOMET, pioglitazone hydrochloride and metformin hydrochloride tablets; MET, metformin; BMI, body mass index; FSH, follicle stimulating hormone; LH, luteinizing hormone; TT, total testosterone; FAI, free androgen index; SHBG, sex hormone-binding globulin; AND, androstenedione; FPG, fasting plasma glucose; FINS, fasting insulin; AUCGlu, area under the glucose curve; AUCIns, area under the insulin curve; HOMA-IR, homeostasis model assessment-insulin resistance; Results are expressed as mean ± SD or median (25th–75th percentile)