Fig. 2

Aberrantly increased expression of FABP5 in GCs of patients and ovaries of mice with PCOS. A Bar plot showing FABP5 mRNA expression in the human primary ovarian GCs of PCOS patients and healthy individuals, as measured by qRT‒PCR (n = 12). B Immunofluorescence staining of FABP5 in human primary ovarian GCs of PCOS patients and healthy individuals. Scale bar, 50 μm. C Bar plot showing the expression of Fabp5 mRNA in the ovaries of mice with PCOS measured by qRT‒PCR (n = 6). D, E Immunoblot plot (D) and bar plot of the statistical analysis (E) showing the expression of FABP5 in the ovaries of mice with PCOS determined by Western blot analysis (n = 4). F Immunohistochemical plot of FABP5 expression and localization in the ovaries of mice with PCOS. A two-tailed unpaired t test was used for all the statistical analyses in this section. ** P < 0.01