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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: Arachidonic acid inhibit granulosa cell function by affecting metabolic function of liver in brown adipose transplantation rats

Fig. 1

Flow chart of the research. S/D rat were treated with saline and DHEA randomly, and divided into control group and PCOS group. After surgery, PCOS group were divided into sham operation (PCOS + sham) group and BAT transplantation (PCOS + BAT) group. Staining was performed to determine the alteration of ovarian and BAT pathology, estrus cycle and glucometabolic phenotypes observation were conducted. And the liver tissue was collected, we detected the changes of liver factors, performed untargeted metabolomics analysis to search differential expression metabolites. Finally, we investigated the function of those metabolites

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