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Table 4 Univariate and multivariate analysis of the factors correlated with progression - free survival (PFS) of HGSOC patients

From: Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway

Variables

Univariate analysis

 

Multivariate analysis

HR

95%CI

p value

 

HR

95%CI

p value

Age (≥ 60)

1.27

0.77–2.11

0.35

    

Tumor size

       

< 5 cm

1

      

5-10 cm

0.81

0.31–2.12

0.25

    

>10 cm

1.93

0.82–4.54

0.13

    

FIGO stage

       

I+II

1

   

1

  

III+IV

3.64

1.44–9.21

< 0.01

 

3.17

1.24–8.10

0.01

TGFBIp expression

3.06

1.77–5.32

< 0.01

 

2.68

1.54–4.66

< 0.01

Ki67 expression

1.40

0.84–2.31

0.19

    

EGFR expression

0.67

0.42–1.08

0.10

    

PDL1 expression

1.29

0.78–2.12

0.32

    
  1. Note: HGSOC: high grade serous ovarian carcinoma