Fig. 6

MEOX1 was Involved in the Proliferation of Ovarian Cancer Cells in vitro and in vivo. A-C The CCK8 assays (A) and the colony formation assays (B-C) revealed the effect of MEOX1 knockdown on the proliferation ability and the colony-forming ability of A2780 cells. D-F The CCK8 assays (D) and the colony formation assays (E–F) determined the effect of MEOX1 overexpression on the proliferation ability and the colony-forming ability of SKOV3 cells. G The images of xenografts harvested at the sacrifice in the sh-MEOX1-1 group, the sh-MEOX1-2 group, and the sh-con group of the nude mice subcutaneous transplant tumor model of ovarian cancer. H. Tumor volume of xenografts in the sh-MEOX1-1 group, the sh-MEOX1-2 group, and the sh-con group, Tumor volume (mm³) = length (mm) × width² (mm²) /2. NS, not statistically significant, *P < 0.05, **P < 0.01, P = 0.09 vs. sh-con; NS, not statistically significant, #P < 0.05, ##P < 0.01 vs. V5-con