Fig. 7
From: Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1
MEOX1 regulated EMT of Ovarian Cancer Cells in vitro. A-B Transwell migration assays were conducted to evaluate the migratory potential of A2780 cells (A) treated with or without MEOX1 suppression and SKOV3 cells (B) treated with or without MEOX1 overexpression. The upper image displayed the migrated cells, and the lower image showed the statistical results of the migrated cell number. C-D Western blot assays were performed to determine the effect of MEOX1 knockdown (C) or overexpression (D) on the expression of E-cadherin and Vimentin proteins in A2780 cells or SKOV3 cells; the lower image showed the statistical results of the protein expression of E-cadherin and Vimentin; *P < 0.05, P = 0.067 vs. sh-con; #P < 0.05 vs. V5-con