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Table 2 Prognostic analysis of 12 candidate LNM-related genes in ovarian cancer

From: Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1

Gene

OS

PFS

HRa ( 95%CIb)

P

HRa ( 95%CIb)

P

TUBA4B

0.84 (0.74, 0.96)

0.010

0.88 (0.78, 1.01)

0.062

SPP1

1.31 (1.16, 1.50)

 < 0.001

1.38 (1.21, 1.57)

 < 0.001

RGS1

0.93 (0.82, 1.06)

0.010

1.25 (1.09, 1.42)

 < 0.001

VTCN1

1.12 (0.97, 1.30)

0.130

1.15 (0.99, 1.33)

0.066

TMPRSS4

0.83 (0.73, 0.95)

0.006

0.83 (0.73, 0.95)

0.008

EPHX4

0.85 (0.69, 1.05)

0.130

1.31 (1.05, 1.65)

0.019

RUNX3

0.83 (0.72, 0.97)

0.019

0.94 (0.82, 1.09)

0.430

MUC16

0.83 (0.73, 0.95)

0.005

1.21 (1.05, 1.41)

0.010

SPON1

0.83 (0.73, 0.94)

0.005

0.91 (0.79, 1.05)

0.210

PCDHB2

1.31 (1.07, 1.62)

0.010

1.49 (1.21, 1.84)

 < 0.001

MEOX1

1.16 (1.02, 1.32)

0.021

1.21 (1.06, 1.38)

0.005

SLC4A11

0.79 (0.64, 0.97)

0.024

1.36 (1.11, 1.68)

0.003

  1. aHazard Ratio; > 1 represents a poor prognostic factor, and < 1 represents a good prognostic factor
  2. bCondifence Interval