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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Methyl 3,4-dihydroxybenzoate alleviates oxidative damage in granulosa cells by activating Nrf2 antioxidant pathway

Fig. 5

MDHB inhibited oxidative stress by promoting Nrf2-mediated antioxidative activity in KGN cells. A The effect of MDHB (0, 5, 10, 20µM) on Nrf2 gene expression by qPCR analysis. B, C Immunoblots showed the expression of Nrf2 and Keap1 in KGN cells treated with MDHB (0, 5, 10, 20µM). Quantification of the protein levels relative to β-actin. D-F qPCR analysis showed the expression of SOD1, NQO1 and GCLC in KGN cells treated with TBHP or MDHB (10, 20µM). All data were presented as the Means ± SD, *P < 0.05, **P < 0.01

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Journal of Ovarian Research

ISSN: 1757-2215

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