Fig. 6

MDHB improves embryo quality of endometriosis mice. A Upper panel showing representative visible lesions within the peritoneal cavity of an endometriosis mice (EM) and an MDHB treated endometriosis mice (EM + MDHB) six weeks after surgery. B Histology confirmed endometriosis. The cystic lesions of EM and EM + MDHB group consisted of single-layered epithelium and underlying stoma with hemosiderin accumulation (black arrows), Scale bar = 100 μm for ×200 images. Scale bar = 50 μm for ×400 images. C The morphology of mouse embryos in blastocyst stage from control(n = 19), EM(n = 18) and EM + MDHB(n = 19) group (scale bar = 200 μm). D The blastocyst formation rate of control, EM and EM + MDHB group. All data were presented as the Means ± SD, ** P < 0.01, *P < 0.05