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New reviewer recruitment

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The Journal of Ovarian Research invites you to join our team of reviewers in assessing manuscripts. For consideration, please send your CV to dana.dovey@biomedcentral.com.

Articles

Featured article

Thy-1 predicts poor prognosis and is associated with self-renewal in ovarian cancer

Ovarian cancer is the leading cause of gynecologic cancer death in the United States despite effective first-line systemic chemotherapy. Cancer stem cells (CSCs) retain the ability to self-renew and proliferate and may be a means of harboring disease that evades standard treatment strategies. We previously performed a high-throughput screen to assess differential protein expression in ovarian CSCs compared to non-CSCs and observed that Thy-1 was more highly expressed in CSCs. Our primary aim was to validate Thy-1 (CD90) as a cancer stem cell (CSC) marker in epithelial ovarian cancer (EOC), correlate with clinical outcomes, and assess as a potential therapeutic target.

Aims and scope

Journal of Ovarian Research is an open access, peer reviewed, online journal that aims to provide a forum for high-quality basic and clinical research on ovarian function, abnormalities, and cancer. The journal focuses on research that provides new insights into ovarian functions as well as prevention and treatment of diseases afflicting the organ.

Topical areas include, but are not restricted to:

  • Ovary development, hormone secretion and regulation
  • Follicle growth and ovulation
  • Infertility and Polycystic ovarian syndrome
  • Regulation of pituitary and other biological functions by ovarian hormones
  • Ovarian cancer, its prevention, diagnosis and treatment
  • Drug development and screening
  • Role of stem cells in ovary development and function

Journal of Ovarian Research is affiliated with the CROWN initiative, Core Outcomes in Women’s Health. CROWN is an international initiative, led by journal editors, to harmonise outcome reporting in women’s health research. We are coming together to address the widespread, unwarranted variation in reporting of outcomes. CROWN’s main aim is to encourage researchers to report core outcome sets for key conditions in women’s health.

Editors-in-Chief

Sham S Kakar, University of Louisville, USA

Benjamin K Tsang, University of Ottawa, Canada

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