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  1. Studies have revealed the implications of cancer-associated fibroblasts (CAFs) in tumor progression, metastasis, and treatment resistance. Here, in silico analyses were performed to reveal the key genes and pa...

    Authors: Li Han, Xiaojuan Guo, Ruijuan Du, Kelei Guo, Pei Qi and Hua Bian
    Citation: Journal of Ovarian Research 2022 15:75
  2. Infertility remains a significant public health concern. An issue with controlled ovarian stimulation (COS) is the selection of an exogenous gonadotropin (Gn) regimen, which is mainly based on urinary follicle...

    Authors: Chunxia Yang, Naijun Dong, Feng Li, Yurong Ji, Yu Pan and Hong She
    Citation: Journal of Ovarian Research 2022 15:74
  3. High grade epithelial ovarian cancer (EOC) represents a diagnostic and therapeutic challenge due to its aggressive features and short recurrence free survival (RFS) after primary treatment. Novel targets to in...

    Authors: Monika Sobočan, Daniela Brunialti, Sussanne Sprung, Christoph Schatz, Jure Knez, Rajko Kavalar, Iztok Takač and Johannes Haybaeck
    Citation: Journal of Ovarian Research 2022 15:73
  4. Among many gynecological malignancies ovarian cancer is the most prominent and leading cause of female mortality worldwide. Despite extensive research, the underlying cause of disease progression and pathology...

    Authors: Anam Beg, Rafat Parveen, Hassan Fouad, M. E. Yahia and Azza S. Hassanein
    Citation: Journal of Ovarian Research 2022 15:72
  5. Highly differentiated follicular carcinoma (HDFCO) is a rare form of struma-derived thyroid-type carcinoma in ovary, defined as ovarian struma spreading beyond ovary but consisting of benign thyroid tissues. N...

    Authors: Yi-Ting Bao, Chao Wang, Wu Huang, Liang-Qing Yao and Lei Yuan
    Citation: Journal of Ovarian Research 2022 15:71
  6. Mitochondrial dynamics (e.g. fission/fusion) play an important role in controlling chemoresistance in representative gynecologic malignancies, ovarian and cervical cancer. Processing the long form of Optic atr...

    Authors: Bao Kong, Chae Young Han, Se Ik Kim, David A. Patten, Youngjin Han, Euridice Carmona, Dar-Bin Shieh, Annie C. Cheung, Anne-Marie Mes-Masson, Mary-Ellen Harper, Yong Sang Song and Benjamin K. Tsang
    Citation: Journal of Ovarian Research 2022 15:70
  7. Dysregulation of Ectonucleoside Triphospahate Diphosphohydrolase 5 (ENTPD5) in tumors might be associated with tumor progression, while the role of ENTPD5 in the growth and metastasis of serous ovarian cancer ...

    Authors: Xueping Chen, Zhiqiang Zha, Yu Wang, Yun Chen, Menglan Pang, Liping Huang and Yao Chen
    Citation: Journal of Ovarian Research 2022 15:69
  8. Mature cystic teratomas of the ovary (MCTO) are a type of germ cell tumor that may contain well-differentiated tissues developed from three germ cell layers and constitute about 20% of ovarian germ cell tumors...

    Authors: Stefano Palomba, Tiziana Russo, Giuseppe Albonico and Marcello Tripodi
    Citation: Journal of Ovarian Research 2022 15:68
  9. Ovarian cancer is composed of a complex system of cells best described by features such as clonal evolution, spatial and temporal genetic heterogeneity, and development of drug resistance, thus making it the m...

    Authors: Patriciu Achimas-Cadariu, Paul Kubelac, Alexandru Irimie, Ioana Berindan-Neagoe and Frank Rühli
    Citation: Journal of Ovarian Research 2022 15:67
  10. Rising evidences bespeak that circular RNAs are indispensable in regulating cellular biological behaviors and engaging in diseases' occurrence. CircRHOBTB3 has been reported to participate intimately in the pr...

    Authors: Yihan Fu and Hong Sun
    Citation: Journal of Ovarian Research 2022 15:66
  11. To evaluate the diagnostic utility of conventional magnetic resonance imaging (MRI)-based characteristics and a texture analysis (TA) for discriminating between ovarian thecoma-fibroma groups (OTFGs) and ovari...

    Authors: Keita Nagawa, Tomoki Kishigami, Fumitaka Yokoyama, Sho Murakami, Toshiharu Yasugi, Yasunobu Takaki, Kaiji Inoue, Saki Tsuchihashi, Satoshi Seki, Yoshitaka Okada, Yasutaka Baba, Kosei Hasegawa, Masanori Yasuda and Eito Kozawa
    Citation: Journal of Ovarian Research 2022 15:65
  12. Circulating leukocytes are an important part of the immune system. The aim of this work is to explore the role of preoperative circulating leukocytes in serous ovarian carcinoma and investigate whether they ca...

    Authors: Ying Feng, Zhixiang Wang, Ran Cui, Meizhu Xiao, Huiqiao Gao, Huimin Bai, Bert Delvoux, Zhen Zhang, Andre Dekker, Andrea Romano, Shuzhen Wang, Alberto Traverso, Chongdong Liu and Zhenyu Zhang
    Citation: Journal of Ovarian Research 2022 15:64
  13. The prognostic value of the expression of estrogen receptor (ER) subtypes ER⍺ and ERβ in ovarian cancer has previously been evaluated by meta-analyses. However, the results are contradictory and controversial.

    Authors: Chun Wai Ng and Kwong-Kwok Wong
    Citation: Journal of Ovarian Research 2022 15:63
  14. Blastomere loss is a common phenomenon that occurs following cryopreservation. To date, studies have drawn conflicting conclusions regarding the impact of blastomere loss on pregnancy outcomes. Besides, limite...

    Authors: Shutian Jiang, Wei Jin, Xinxi Zhao, Qianwen Xi, Li Chen, Yining Gao, Wenzhi Li and Yanping Kuang
    Citation: Journal of Ovarian Research 2022 15:62
  15. Emerging evidence identifies enhancer RNAs (eRNAs) as a class of regulatory ncRNAs that can contribute to the transcription of target genes. In this study, we used an integrated data analysis method to identif...

    Authors: Jiaya Mo, Lianghao Zhang, Huiqing Li, Haoran Duan, Dong Wang, Xiaolei Zhao and Ya Xie
    Citation: Journal of Ovarian Research 2022 15:61
  16. Women with an elevated basal FSH indicate diminished ovarian reserve and reduced oocyte and embryo numbers. DMSCs are likely to be involved in immune tolerance of pregnancy maintenance. We investigate the effe...

    Authors: Yi-bo He, Li Zhang, Lin-li Zhou, Yi-min Chen, Jia-hong Lu, Jie Chen and Yong-lin Liu
    Citation: Journal of Ovarian Research 2022 15:60
  17. Greater ovulatory years is associated with increased ovarian cancer risk. Although ovulation leads to an acute pro-inflammatory local environment, how long-term exposure to ovulation impacts ovarian carcinogen...

    Authors: Naoko Sasamoto, Paul A. Stewart, Tianyi Wang, Sean J. Yoder, Srikumar Chellappan, Jonathan L. Hecht, Brooke L. Fridley, Kathryn L. Terry and Shelley S. Tworoger
    Citation: Journal of Ovarian Research 2022 15:59
  18. Circular RNA (circRNA), a class of RNA with a covalent closed circular structure that widely existed in serum and plasma, has been considered an ideal liquid biopsy marker in many diseases. In this study, we e...

    Authors: Lili Ge, Yu Sun, Yaqian Shi, Guangquan Liu, Fang Teng, Zhe Geng, Xiyi Chen, Hanzi Xu, Juan Xu and Xuemei Jia
    Citation: Journal of Ovarian Research 2022 15:58
  19. Among reproductive cancers, ovarian cancer leads to the highest female mortality rate. Fisetin, a natural flavonoid, exerts pharmacological effects, inhibiting cancer growth with various origins. Although mult...

    Authors: Yaxian Liu, Hongwen Cao, Yanhui Zhao, Lijuan Shan and Shuhai Lan
    Citation: Journal of Ovarian Research 2022 15:57
  20. Increasing evidence has indicated that Maelstrom (MAEL) plays an oncogenic role in various human carcinomas. However, the exact function and mechanisms by which MAEL acts in epithelial ovarian cancer (EOC) rem...

    Authors: Wei-Peng He, Gui-Ping Yang, Zun-Xian Yang, Hong-Wei Shen, Ze-Shan You and Guo-Fen Yang
    Citation: Journal of Ovarian Research 2022 15:55
  21. Ovarian cancer (OVC) is a devastating disease worldwide; therefore the identification of prognostic biomarkers is urgently needed. We aimed to determine a robust microRNA signature-based risk score system that...

    Authors: Min Zhou, Tao Wu, Yuan Yuan, Shu-Juan Dong, Zhi-Ming Zhang, Yan Wang and Jing Wang
    Citation: Journal of Ovarian Research 2022 15:54
  22. Ovarian insufficiency is a major concern for long-term cancer survivors. Ovarian tissue cryopreservation for fertility preservation is an emerging technique that has proven successful over the past decade thro...

    Authors: Anna K. Dietl, Ralf Dittrich, Inge Hoffmann, Dominik Denschlag, Aida Hanjalic-Beck, Andreas Müller, Matthias W. Beckmann and Laura Lotz
    Citation: Journal of Ovarian Research 2022 15:53
  23. Previous studies have revealed that miRNAs participate in the pathogenesis of ovarian cancer; however, whether miR-600 is also involved remains unclear. In this study, we aimed to investigated the role of miR-...

    Authors: Lili Shan, Pingping Song, Yangyang Zhao, Na An, Yanqiu Xia, Yue Qi, Hongyan Zhao and Jing Ge
    Citation: Journal of Ovarian Research 2022 15:52
  24. Patients treated with neoadjuvant chemotherapy (NACT) for advanced high-grade serous ovarian carcinoma (HGSC) have a higher rate and shorter time to platinum-resistant recurrence compared to patients treated w...

    Authors: Zibi Marchocki, Alicia Tone, Carl Virtanen, Richard de Borja, Blaise Clarke, Theodore Brown and Taymaa May
    Citation: Journal of Ovarian Research 2022 15:50
  25. Accumulated studies have provided controversial evidences of expression patterns and prognostic value of the GATA family in human ovarian cancer. In the present study, we accessed the distinct expression and prog...

    Authors: Quan Zhou, Huai-jie Yang, Man-zhen Zuo and Ya-ling Tao
    Citation: Journal of Ovarian Research 2022 15:49
  26. Taxol resistance in serous ovarian cancer is responsible for its poor prognosis, yet the underlying mechanism is still poorly understood. Thus, we probed the mechanism of Taxol resistance in serous ovarian can...

    Authors: Yuqing Shen, Hui Lin, Kelie Chen, Wanzhong Ge, Dajing Xia, Yihua Wu and Weiguo Lu
    Citation: Journal of Ovarian Research 2022 15:48
  27. The Ayurvedic system of medicine mentions the use of seeds of Bryonopsis laciniosa (L.) Naud. (also known as Shivlingi due to their unique structure resembling a ‘Shivling’) for treating sexual dysfunction, impai...

    Authors: Acharya Balkrishna, Pradeep Nain, Monali Joshi, Brijesh Kumar and Anurag Varshney
    Citation: Journal of Ovarian Research 2022 15:46
  28. Despite several initiatives by research groups, regulatory authorities, and scientific associations to engage citizens/patients in clinical research, there are still obstacles to participation. Among the main ...

    Authors: Paola Mosconi, Anna Roberto, Nicoletta Cerana, Nicoletta Colombo, Florence Didier, Maurizio D’Incalci, Domenica Lorusso and Fedro Alessandro Peccatori
    Citation: Journal of Ovarian Research 2022 15:45
  29. Currently, there is no universal criteria for the trigger time of controlled ovarian hyperstimulation (COH), especially with the emerging depot GnRH agonist protocol. It is challenging to explore an indicator ...

    Authors: Houming Su, Youhua Lai, Jie Li, Tingting Liao, Licheng Ji, Xinyao Hu and Kun Qian
    Citation: Journal of Ovarian Research 2022 15:44
  30. To investigate the alterations of peripheral lymphocyte subpopulations in ovarian cancer patients compared to benign or borderline counterparts. The possible clinicopathological implications were also evaluated.

    Authors: Shuang Ye, Wei Chen, Yuwei Zheng, Yutuan Wu, Libing Xiang, Teng Li, Bo Ping, Xiaoming Zhang and Huijuan Yang
    Citation: Journal of Ovarian Research 2022 15:43
  31. Resistant ovary syndrome (ROS) is a rare endocrine disorder and there have been few reports of live births by affected patients. As gonadotropin resistance leads immature oocytes, some researchers reported few...

    Authors: Huiying Li, Tianli Chang, Hongbei Mu and Wenpei Xiang
    Citation: Journal of Ovarian Research 2022 15:42
  32. Ovarian “seromucinous carcinoma” has been recently removed in 2020 5th Edition of WHO classification of Female Genital Tumors and is considered as a subtype of endometrioid carcinoma with mucinous differentiation...

    Authors: Bo Seong Yun, Seyeon Won, Ju-Hyun Kim, Nara Lee, Miseon Kim, Mi Kyoung Kim, Mi-La Kim, Yong Wook Jung, Ji Young Kim, Seok Ju Seong and Eunah Shin
    Citation: Journal of Ovarian Research 2022 15:41
  33. Polycystic ovary syndrome (PCOS) is an endocrine disease associated with reproduction. The Cuscuta-Salvia formula has been widely used to treat for PCOS in clinic. However, its chemical and pharmacological proper...

    Authors: Ying-ying Zhang, Jian-xiong Ma, Yu-tian Zhu, Yi-xuan Wang, Wang-qiang Chen, Xin Sun, Wei Zhang, Chen-ye Wang and Cai-fei Ding
    Citation: Journal of Ovarian Research 2022 15:40
  34. Ovarian cancer (OC) is the deadliest tumor in the female reproductive tract. And increased resistance to platinum-based chemotherapy represents the major obstacle in the treatment of OC currently. Robust and a...

    Authors: Siyu Chen, Yong Wu, Simin Wang, Jiangchun Wu, Xiaohua Wu and Zhong Zheng
    Citation: Journal of Ovarian Research 2022 15:39
  35. Oocyte maturation arrest at metaphase I leads to fertilization failure in humans. In early embryos, the tubulin beta 8 class VIII (TUBB8) encodes a β-tubulin isotype and aids in the assembling of the human oocyte...

    Authors: Zhongyuan Yao, Jun Zeng, Huimin Zhu, Jing Zhao, Xiaoxia Wang, Qiuping Xia, Yanping Li and Lingqian Wu
    Citation: Journal of Ovarian Research 2022 15:38
  36. What influence does seven days of oestrogen administration versus fourteen days have on the reproductive outcomes of frozen-thawed embryo transfer (FET) in programmed endometrial preparation cycles?

    Authors: Wen-Jing Jiang, Jing-Yan Song and Zhen-Gao Sun
    Citation: Journal of Ovarian Research 2022 15:36
  37. Brain-derived neurotrophic factor (BDNF) is a known regulator of the development and maintenance of chronic pain in various chronic disorders. Together with its high-affinity tyrosine kinase type B (TrKB) rece...

    Authors: Sha Wang, Hua Duan, Bohan Li, Wei Hong, Xiao Li, Yiyi Wang and Zheng Chen Guo
    Citation: Journal of Ovarian Research 2022 15:35
  38. The mammalian follicle is the basic functional unit of the ovary, and its normal development is required to obtaining oocytes capable of fertilization. As women get older or decline in ovarian function due to ...

    Authors: Huiying Fan, Jiahuan He, Yucheng Bai, Qina He, Tongwei Zhang, Junya Zhang, Guang Yang, Ziwen Xu, Jingyi Hu and Guidong Yao
    Citation: Journal of Ovarian Research 2022 15:34
  39. Ovarian endometrioma is a common gynecologic disease among reproductive-aged women. Pregnancy-related hormonal status may lead to changes of decidualization, which may resemble ovarian malignancies in sonograp...

    Authors: Min Yin, Tao Wang, Sijian Li, Xinyue Zhang and Jiaxin Yang
    Citation: Journal of Ovarian Research 2022 15:33
  40. Ovarian cancer is one of the most lethal malignancies, with a 1.9% mortality rate worldwide. The dysregulation of the FEN1 gene and miR-4324 has been associated with cancer progression. However, the relationship ...

    Authors: Haixia Wu, Youliang Yan, Jialin Yuan, Mengze Luo and Yingjian Wang
    Citation: Journal of Ovarian Research 2022 15:32
  41. Premature ovarian insufficiency (POI) plagues 1% of women under 40, while quite a few remain an unknown cause. The development of sequencing has helped find pathogenic genes and reveal the relationship between...

    Authors: Jie Li, Tianliu Peng, Le Wang, Panpan Long, Ruping Quan, Hangjing Tan, Minghua Zeng, Xue Wu, Junting Yang, Hongmei Xiao and Xiaobo Shi
    Citation: Journal of Ovarian Research 2022 15:31
  42. Accumulating evidence suggests a strong association between polycystic ovary syndrome (PCOS) and ovarian cancer (OC), but the potential molecular mechanism remains unclear. In this study, we identified previou...

    Authors: Juan Zou, Yukun Li, Nianchun Liao, Jue Liu, Qunfeng Zhang, Min Luo, Jiao Xiao, Yanhua Chen, Mengjie Wang, Kexin Chen, Juan Zeng and Zhongcheng Mo
    Citation: Journal of Ovarian Research 2022 15:30
  43. Measurement of serum CA125, an antigenic fragment of human mucin 16 (MUC16), is used to monitor the clinical progression of epithelial ovarian cancer (EOC). However, rather than simply a passive marker reflect...

    Authors: Kornél Lakatos, Germán González, Jawad Hoballah, Jeff Brooker, Sinyoung Jeong, Conor Evans, Petra Krauledat, W. Peter Hansen, Kevin M. Elias, Manish Patankar, Vilmos Fülöp, Panagiotis A. Konstantinopoulos and Daniel W. Cramer
    Citation: Journal of Ovarian Research 2022 15:28
  44. Ovarian cancer (OC) is one of the serious threats to the health of women worldwide, and accurate biomarkers are urgently demanded for early diagnosis of OC. We have previously confirmed that miR-205 promotes t...

    Authors: Zehua Zhu, Zhaojun Chen, Mingxing Wang, Min Zhang, Yiwen Chen, Xiao Yang, Changjun Zhou, Yuhua Liu, Liquan Hong and Lahong Zhang
    Citation: Journal of Ovarian Research 2022 15:27
  45. Recently, long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) have been identified as essential biomarkers during development of malignancies. This study was performed to study the roles of lncRNA opa-intera...

    Authors: Yujue Wang, Lingling Li, Xun Zhang and Xiaolan Zhao
    Citation: Journal of Ovarian Research 2022 15:25

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