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  1. Poly (ADP)-ribose polymerase (PARP) inhibitors have entered routine clinical practice for the treatment of high-grade serous ovarian cancer (HGSOC), yet the molecular mechanisms underlying treatment response t...

    Authors: Alexandra Franz, Fabian Coscia, Ciyue Shen, Lea Charaoui, Matthias Mann and Chris Sander

    Citation: Journal of Ovarian Research 2021 14:140

    Content type: Research

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  2. A frozen section diagnosis of a borderline ovarian tumor with suspicious features of invasive carcinoma (“at least borderline” or synonymous descriptions) presents us with the dilemma of whether or not to perf...

    Authors: Koen De Decker, Karina H. Jaroch, Joost Bart, Loes F. S. Kooreman, Roy F. P. M. Kruitwagen, Hans W. Nijman and Arnold-Jan Kruse

    Citation: Journal of Ovarian Research 2021 14:139

    Content type: Research

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  3. Accumulating data have established that microRNAs (miRNAs) play significant regulatory roles in the carcinogenesis and progression of ovarian cancer (OC). MiR-425-5p was reported to function in various tumors. Ho...

    Authors: Zhihui Wu, Jianlin Guo, Ying Zhang, Jianhua Liu, Hongping Ma and Yurong Tang

    Citation: Journal of Ovarian Research 2021 14:138

    Content type: Research

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  4. Mixed cell ovarian adenocarcinoma (MCOA) is a malignant gynecologic tumor consisting of serous, mucous, and papillary tumor cells. However, the clinical features and prognosis of MCOA patients are unclear.

    Authors: Huijie Wu, Shaotao Jiang, Peiwen Zhong, Weiru Li and Siyou Zhang

    Citation: Journal of Ovarian Research 2021 14:137

    Content type: Research

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  5. Ovarian cancer is an aggressive tumor in women with high mortality. Paclitaxel (PTX) can be used for the chemotherapy of ovarian cancer. Here, the roles of circular_0061140 (circ_0061140) in PTX sensitivity an...

    Authors: Jun Zhu, Jun-e Luo, Yurong Chen and Qiong Wu

    Citation: Journal of Ovarian Research 2021 14:136

    Content type: Research

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  6. The polycystic ovary syndrome (PCOS) is the most common endocrine associated with insulin resistance, even in the absence of overweight. The global lipid profile of the follicular fluid in PCOS with normal wei...

    Authors: Yanna Ban, Haiying Ran, Ying Chen and Li Ma

    Citation: Journal of Ovarian Research 2021 14:135

    Content type: Research

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  7. Polycystic ovary syndrome (PCOS), as one of the significant endocrine disorders, is common among women worldwide. Food insecurity (FI) and unhealthy dietary patterns can negatively affect reproductive health. ...

    Authors: Mahtab Badri-Fariman, Amirmansour Alavi Naeini, Khadijeh Mirzaei, Ashraf Moeini, Mostafa Hosseini, Seyedeh Elaheh Bagheri and Milad Daneshi-Maskooni

    Citation: Journal of Ovarian Research 2021 14:134

    Content type: Research

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  8. The ovaries are the core reproductive organs in women and are critical for maintaining normal reproductive function and endocrine system stability. An ageing C57 mouse model was used to evaluate the efficacy a...

    Authors: Xing-Hua Pan, Xue-Juan Zhang, Xiang Yao, Ni-Ni Tian, Zai-Ling Yang, Kai Wang, Xiang-Qing Zhu, Jing Zhao, Jie He, Xue-Min Cai, Rong-Qing Pang and Guang-Ping Ruan

    Citation: Journal of Ovarian Research 2021 14:133

    Content type: Research

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  9. Sentinel lymph node (SLN) detection in ovarian cancer is feasible when tracers are injected before the pathological ovary is resected. This study aims to investigate whether the SLN identification is also feas...

    Authors: Pim Laven, Roy Kruitwagen, Petra Zusterzeel, Brigitte Slangen, Toon van Gorp, Jochem van der Pol and Sandrina Lambrechts

    Citation: Journal of Ovarian Research 2021 14:132

    Content type: Brief communication

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  10. The most common gynecologic cancers detected in women in Turkey are uterine cancer, ovarian cancer, and cervical cancer. These data reported that a mean of 3800 individuals were diagnosed with uterine cancer, ...

    Authors: Arash Adamnejad Ghafour, Demet Akdeniz Odemis, Seref Bugra Tuncer, Busra Kurt, Mukaddes Avsar Saral, Seda Kilic Erciyas, Ozge Sukruoglu Erdogan, Betul Celik, Pinar Saip and Hulya Yazici

    Citation: Journal of Ovarian Research 2021 14:131

    Content type: Research

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  11. Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in the women at their reproductive age. Nowadays, the use of herbal compounds for lesser side effects, as compared to drug treatme...

    Authors: Vahid Maleki, Amir Hossein Faghfouri, Fatemeh Pourteymour Fard Tabrizi, Jalal Moludi, Sevda Saleh-Ghadimi, Hamed Jafari-Vayghan and Shaimaa A. Qaisar

    Citation: Journal of Ovarian Research 2021 14:130

    Content type: Review

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  12. Epithelial ovarian cancer (EOC) is a heterogeneous disease with diverse clinicopathological features and behaviors, and its heterogeneity may be concerned with the accumulation of multiple somatic oncogenic mu...

    Authors: Takafumi Watanabe, Hideaki Nanamiya, Yuta Endo, Manabu Kojima, Shinji Nomura, Shigenori Furukawa, Shu Soeda, Hirosumi Tamura, Masae Ryufuku, Daisuke Tanaka, Takao Isogai, Jun-ichi Imai, Shinya Watanabe and Keiya Fujimori

    Citation: Journal of Ovarian Research 2021 14:129

    Content type: Research

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  13. Drug resistance and recurrence are main contributors to the poor prognosis of ovarian cancer. Cisplatin is a platinum compound which is widely used in the treatment of various solid tumors including ovarian ca...

    Authors: Yixuan Liu, Keyu Zhu, Xiaolin Guan, Suhong Xie, Yanchun Wang, Ying Tong, Lin Guo, Hui Zheng and Renquan Lu

    Citation: Journal of Ovarian Research 2021 14:128

    Content type: Research

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  14. Infections by the SARS-CoV-2 virus causing COVID-19 are presently a global emergency. The current vaccination effort may reduce the infection rate, but strain variants are emerging under selection pressure. Th...

    Authors: Santosh Kumar Singh, Shailesh Singh and Rajesh Singh

    Citation: Journal of Ovarian Research 2021 14:126

    Content type: Research

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  15. Polycystic ovary syndrome (PCOS) is the most common endocrinopathies affecting the early reproductive age in women, whose pathophysiology perplexes many researchers till today. This syndrome is classically cat...

    Authors: Hiral Chaudhary, Jalpa Patel, Nayan K. Jain and Rushikesh Joshi

    Citation: Journal of Ovarian Research 2021 14:125

    Content type: Review

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  16. There is an urgent need to set up a useful biomarker for ovarian cancer. Galectin-1 is a promising carbohydrate-binding protein which plays a remarkable role in various malignancies yet its clinical significan...

    Authors: Mahak Masoodi, Zafar A. Shah, Afaq H. Beigh, Sheikh Zahoor Ahmad, Abdul Wahid Mir, Besina Yasin, Roohi Rasool, Khalid Z. Masoodi and Gull Mohammad Bhat

    Citation: Journal of Ovarian Research 2021 14:123

    Content type: Research

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  17. Serous ovarian cancer (SOC) is the most common women cancer and the leading cause of cancer-related mortality among the gynaecological malignancies. Although effective chemotherapeutics combined with surgery a...

    Authors: Jing Zhang, Suhong Xie, Lei Zhou, Xiaoyu Tang, Xiaolin Guan, Minjie Deng, Hui Zheng, Yanchun Wang, Renquan Lu and Lin Guo

    Citation: Journal of Ovarian Research 2021 14:122

    Content type: Research

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  18. Ovarian cancer is the most lethal gynecologic malignancy worldwide. Olaparib, an inhibitor of poly (ADP-ribose) polymerase (PARP), is becoming widely used in ovarian cancer treatment. The overall survival of o...

    Authors: Wenjing Hu, Min Li, Youguo Chen and Xinxian Gu

    Citation: Journal of Ovarian Research 2021 14:121

    Content type: Research

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  19. Currently, there is no effective treatment for premature ovarian failure (POF), and stem cell therapy is considered the most promising treatment. Human umbilical cord blood mesenchymal stem cells (hUC-MSCs) ha...

    Authors: Xiaodan Lv, Chunyi Guan, Ying Li, Xing Su, Lu Zhang, Xueqin Wang, Hong-Fei Xia and Xu Ma

    Citation: Journal of Ovarian Research 2021 14:119

    Content type: Research

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  20. Circular RNAs (circRNAs) are gradually reported to be implicated in the development of malignant tumors, including ovarian cancer (OC). This paper intended to explore the function and action mechanism of hsa_c...

    Authors: Xuan Zhou, Jinchi Jiang and Shuaishuai Guo

    Citation: Journal of Ovarian Research 2021 14:118

    Content type: Research

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  21. The aim of this study was to investigate whether pH is stable when transporting ovarian tissue in media buffered with either HEPES or histidine. Furthermore, if the choice of transport media impacts the in vit...

    Authors: Susanne Elisabeth Pors, Stine Gry Kristensen, Dmitry Nikiforov, Linn Salto Mamsen, Jesus Cadenas, Vinnie Hornshøj Greve, Margit Dueholm and Claus Yding Andersen

    Citation: Journal of Ovarian Research 2021 14:116

    Content type: Brief communication

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  22. Tumor microenvironment and chemokines play a significant role in cancer chemoresistance. This study was designed to reveal the important role of CXCL2 in platinum resistance in epithelial ovarian cancer (EOC)....

    Authors: Sipei Nie, Yicong Wan, Hui Wang, Jinhui Liu, Jing Yang, Rui Sun, Huangyang Meng, Xiaolin Ma, Yi Jiang and Wenjun Cheng

    Citation: Journal of Ovarian Research 2021 14:115

    Content type: Research

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  23. Inguinal hernia containing ovary and fallopian tube can be found in paediatric population and is a rare finding in women of reproductive age group. Most of the cases are associated with congenital abnormalitie...

    Authors: Rahul Saini, Lovenish Bains, Tarangpreet Kaur, Pawan Lal, Veer Pal, Mohd Yasir Beg and Daljit Kaur

    Citation: Journal of Ovarian Research 2021 14:114

    Content type: Case report

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  24. To investigate changes in peripheral lymphocyte subsets after splenectomy during cytoreductive surgery for advanced or recurrent ovarian cancers.

    Authors: Wei Chen, Shuang Ye, Yutuan Wu, Xuan Pei, Libing Xiang, Bo Ping, Boer Shan and Huijuan Yang

    Citation: Journal of Ovarian Research 2021 14:113

    Content type: Research

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  25. Recent studies have consistently shown that AFC and serum AMH are good predictors of ovarian response and have shown strong correlations. However, it is not unusual for reproductive medicine specialists to enc...

    Authors: Yaxin Guo, Huahua Jiang, Shiqiao Hu, Shuai Liu, Fei Li and Lei Jin

    Citation: Journal of Ovarian Research 2021 14:111

    Content type: Research

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  26. Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) were reported to be aberrantly expressed and related to the pathogenesis of ovarian cancer. However, the role and regulatory mechanism of MSC-AS1 in ovaria...

    Authors: Yinling Zhao, Donglan Yuan, Dandan Zhu, Tianhui Xu, Aihua Huang, Li Jiang, Chiwen Liu, Hua Qian and Xinhua Bu

    Citation: Journal of Ovarian Research 2021 14:109

    Content type: Research

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  27. Ovarian Carcinoma (OCa) is a high-mortality malignancy derived from female reproductive system. Increasing evidence has identified long non-coding RNAs (lncRNAs) as important regulators in OCa chemoresistance....

    Authors: Yao Li, Yan Zhai and Yuxuan Chen

    Citation: Journal of Ovarian Research 2021 14:108

    Content type: Research

    Published on:

  28. Increasing evidence supported an association between cancer and coagulation system. We aimed to identify prognostic values of coagulation biomarkers in epithelial ovarian cancer (EOC).

    Authors: Jiani Yang, Yue Jin, Shanshan Cheng, Chao Wang, Nan Zhang, Shan Huang, Yaqian Zhao and Yu Wang

    Citation: Journal of Ovarian Research 2021 14:106

    Content type: Research

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  29. Citation: Journal of Ovarian Research 2021 14:105

    Content type: Correction

    Published on:

    The original article was published in Journal of Ovarian Research 2021 14:97

  30. Preimplantation genetic testing (PGT) is offered to a wide range of structural and numerical chromosomal imbalances, with PGT- polymerase chain reaction (PCR), as the method of choice for amplifying the small ...

    Authors: Adva Aizer, Noa Harel-Inbar, Hagit Shani and Raoul Orvieto

    Citation: Journal of Ovarian Research 2021 14:104

    Content type: Brief communication

    Published on:

  31. Copy number variation (CNVs) is a key factor in breast cancer development. This study determined prognostic molecular characteristics to predict breast cancer through performing a comprehensive analysis of cop...

    Authors: Wei Hu, Mingyue Li, Qi Zhang, Chuan Liu, Xinmei Wang, Jing Li, Shusheng Qiu and Liang Li

    Citation: Journal of Ovarian Research 2021 14:103

    Content type: Research

    Published on:

  32. The ovarian reserve is one of the most important indicators of female fertility. It allows for the evaluation of the number of viable oocytes. This parameter is actively used in pregnancy planning and in assis...

    Authors: Aleksandra V. Moiseeva, Varvara A. Kudryavtseva, Vladimir N. Nikolenko, Marine M. Gevorgyan, Ara L. Unanyan, Anastassia A. Bakhmet and Mikhail Y. Sinelnikov

    Citation: Journal of Ovarian Research 2021 14:102

    Content type: Review

    Published on:

  33. The design of this study was due to the report of the antioxidant properties of Ellagic acid (EA) for its evaluation on the Insulin resistance (IR), oxidative stress and sex hormones levels in women with polyc...

    Authors: Mahnaz Kazemi, Fatemeh Lalooha, Mohammadreza Rashidi Nooshabadi, Fariba Dashti, Maria Kavianpour and Hossein Khadem Haghighian

    Citation: Journal of Ovarian Research 2021 14:100

    Content type: Research

    Published on:

  34. Ovarian cancer is usually diagnosed at an advanced stage due to its early asymptomatic course and late-stage non-specific symptoms. This highlights the importance of researching the molecular mechanisms involv...

    Authors: Argelia Calvillo-Robledo, Enrique Pedernera, Flavia Morales-Vásquez, Delia Pérez-Montiel, María J. Gómora, Miguel Ángel Almaraz, Paulina García de Alba Graue, Elizabeth Rendón, Horacio Noé López-Basave, Andrés Quintanar-Stephano and Carmen Méndez

    Citation: Journal of Ovarian Research 2021 14:98

    Content type: Research

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  35. Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder of heterogeneous nature. Secreted frizzled-related protein (SFRP) 5 is an anti-inflammatory adipokine implicated in metabolic homeostasis. We ai...

    Authors: Yi Zhang, Yuxin Ran, Lingna Kong, Lihong Geng, Hua Huang, Hongying Zhang, Jun Hu, Hongbo Qi and Ying Chen

    Citation: Journal of Ovarian Research 2021 14:97

    Content type: Research

    Published on:

    The Correction to this article has been published in Journal of Ovarian Research 2021 14:105

  36. Ovarian cancer (OC) is considered the most lethal gynecological cancer, of which more than 65% cases are diagnosed in advanced stages, requiring platinum-based neoadjuvant chemotherapy (NACT).

    Authors: Jorge A. Alegría-Baños, José C. Jiménez-López, Arely Vergara-Castañeda, David F. Cantú de León, Alejandro Mohar-Betancourt, Delia Pérez-Montiel, Gisela Sánchez-Domínguez, Mariana García-Villarejo, César Olivares-Pérez, Ángel Hernández-Constantino, Acitlalin González-Santiago, Miguel Clara-Altamirano, Liz Arela-Quispe and Diddier Prada-Ortega

    Citation: Journal of Ovarian Research 2021 14:96

    Content type: Research

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  37. Cryopreservation and transplantation of ovarian tissue (OTCTP) represent a promising fertility preservation technique for prepubertal patients or for patients requiring urgent oncological management. However, ...

    Authors: Carmen Terren, Michelle Nisolle and Carine Munaut

    Citation: Journal of Ovarian Research 2021 14:95

    Content type: Research

    Published on:

  38. Laser-assisted hatching (LAH) has been widely applied to facilitate blastocyst hatching in IVF-ET treatment, however, the effect of LAH on subsequent development and clinical outcomes of the lower grade cleava...

    Authors: Weihai Xu, Ling Zhang, Lin Zhang, Zhen Jin, Limei Wu, Shishi Li and Jing Shu

    Citation: Journal of Ovarian Research 2021 14:94

    Content type: Research

    Published on:

  39. The aim of this meta-analysis was to assess the effectiveness and safety of secondary cytoreductive surgery plus chemotherapy (SCS + CT) in recurrent ovarian cancer (ROC). Our secondary purpose was to analyze ...

    Authors: Ting Ding, Dan Tang and Mingrong Xi

    Citation: Journal of Ovarian Research 2021 14:93

    Content type: Review

    Published on:

  40. Ovarian cancer is one of the most common gynecological tumors, and among gynecological tumors, its incidence and mortality rates are fairly high. However, the pathogenesis of ovarian cancer is not clear. The p...

    Authors: Cuicui Dong, Xin Tian, Fucheng He, Jiayi Zhang, Xiaojian Cui, Qin He, Ping Si and Yongming Shen

    Citation: Journal of Ovarian Research 2021 14:92

    Content type: Research

    Published on:

  41. Biochemical recurrence is defined as only rising CA-125 but no radiographic evidence of disease; noteworthily, it generally precedes the onset of clinical evidence. Now treatment strategies of biochemical recu...

    Authors: Zhongyu Wang, Yake Huang, Ling Long, Li Zhou, Yan Huang, Lei Gan, Aimin Pu, Sufen Li and Rongkai Xie

    Citation: Journal of Ovarian Research 2021 14:91

    Content type: Research

    Published on:

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