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  1. Fragile X premutation (Amplification of CGG number 55–200) is associated with increased risk for fragile X-Associated Premature Ovarian Insufficiency (FXPOI) in females and fragile X-associated tremor/ataxia s...

    Authors: M. Friedman-Gohas, S. E. Elizur, O. Dratviman-Storobinsky, A. Aizer, J. Haas, H. Raanani, R. Orvieto and Y. Cohen

    Citation: Journal of Ovarian Research 2020 13:22

    Content type: Research

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  2. Recent studies have suggested that estrogen (E2) plays an important role in epithelial ovarian cancer (EOC). However, the mechanism of E2 in ovarian cancers is unclear. The purpose of this study was to investi...

    Authors: Shengnan Li, Kuo Jiang, Jia Li, Xiaohua Hao, Wenguang Chu, Ceng Luo, Yuanyuan Zhu, Rougang Xie and Biliang Chen

    Citation: Journal of Ovarian Research 2020 13:20

    Content type: Research

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  3. The aim of this study was to explore the clinicopathological characteristics of recurrent adult-type granulosa cell tumor of the ovary (AGCOT) and evaluated the treatment results to define the prognostic param...

    Authors: Dan Zhao, Yanan Zhang, Zhengjie Ou, Rong Zhang, Shan Zheng and Bin Li

    Citation: Journal of Ovarian Research 2020 13:19

    Content type: Research

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  4. PPOS protocols, initially described for FP in women with cancer, have many advantages compared to antagonist protocols. PPOS protocols were not evaluated for women with endometriosis. The objective of the stud...

    Authors: Emmanuelle Mathieu d’Argent, Clément Ferrier, Chrysoula Zacharopoulou, Naouel Ahdad-Yata, Anne-Sophie Boudy, Adèle Cantalloube, Rachel Levy, Jean-Marie Antoine, Emile Daraï and Sofiane Bendifallah

    Citation: Journal of Ovarian Research 2020 13:18

    Content type: Research

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  5. The aim of this study is to establish a noninvasive preoperative model for predicting primary optimal cytoreduction in advanced epithelial ovarian cancer by HE4 and CA125 combined with clinicopathological para...

    Authors: Li-yuan Feng, Sheng-bin Liao and Li Li

    Citation: Journal of Ovarian Research 2020 13:17

    Content type: Research

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  6. Cancer stem cells (CSCs) can self-renew, proliferate into differentiated cells, or enter a quiescent state and are regarded to cause chemoresistance and recurrence. An integrative analysis of transcription fac...

    Authors: Hyun Park, Sohyun Hwang, Ju-Yeon Jeong, Sang Geun Jung, Min Chul Choi, Won Duk Joo, Seung Hun Song, Chan Lee and Hee Jung An

    Citation: Journal of Ovarian Research 2020 13:16

    Content type: Research

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  7. DCN (decorin) is a proteoglycan known to be involved in regulating cell proliferation, collagen fibril organization and migration. In our global transcriptome RNA-sequencing approach to systematically identify ne...

    Authors: A. Kedem, K. Ulanenko-Shenkar, Y. Yung, G. M. Yerushalmi, E. Maman and A. Hourvitz

    Citation: Journal of Ovarian Research 2020 13:15

    Content type: Research

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  8. Bevacizumab and gemcitabine are key drugs for treating recurrent epithelial ovarian cancer. However, information about the combination of bevacizumab and gemcitabine is insufficient. We conducted a phase II st...

    Authors: Shoji Nagao, Ai Kogiku, Kazuhiro Suzuki, Takashi Shibutani, Kasumi Yamamoto, Tomoatsu Jimi, Miho Kitai, Takaya Shiozaki, Kazuko Matsuoka and Satoshi Yamaguchi

    Citation: Journal of Ovarian Research 2020 13:14

    Content type: Research

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  9. We elucidated the role of specific MicroRNAs (miRNAs) in the development of polycystic ovary syndrome (PCOS) and explained the changes in the proliferation of granulosa cells. Excised ovarian cortex specimens ...

    Authors: Zhengfang Xiong, Bing Li, Wenjuan Wang, Xianghui Zeng, Binye Li, Shengyan Jian and Liyun Wang

    Citation: Journal of Ovarian Research 2020 13:13

    Content type: Research

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  10. Degeneration of ovarian function is an obvious feature of female aging. In addition, studies have shown that autophagy decreases with age, and DNA methylation is a hallmark epigenetic pattern during aging. How...

    Authors: Qiuyuan Li, Minghui Cai, Jiao Wang, Qiang Gao, Xiaocheng Guo, Xiaotong Jia, Shanshan Xu and Hui Zhu

    Citation: Journal of Ovarian Research 2020 13:12

    Content type: Research

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  11. Polycystic ovary syndrome (PCOS) is a polygenic endocrine disorder and the most common gynecological endocrinopathy among reproductive-aged women. Current remedies are often used only to control its signs and ...

    Authors: Fatemeh Pourteymour Fard Tabrizi, Fatemeh Hajizadeh-Sharafabad, Maryam Vaezi, Hamed Jafari-Vayghan, Mohammad Alizadeh and Vahid Maleki

    Citation: Journal of Ovarian Research 2020 13:11

    Content type: Review

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  12. Ovarian cancer (OC) ranks fifth as a cause of gynecological cancer-associated death globally. Until now, the molecular mechanisms underlying the tumorigenesis and prognosis of OC have not been fully understood...

    Authors: Dan Yang, Yang He, Bo Wu, Yan Deng, Nan Wang, Menglin Li and Yang Liu

    Citation: Journal of Ovarian Research 2020 13:10

    Content type: Research

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  13. The limitation of current biomarker of early stage ovarian cancer and the anatomical location of ovarian (depths of the pelvic) make ovarian cancer difficult to be detected in early stage. Growing evidence sho...

    Authors: Lin Cheng, Kun Zhang, Yunan Qing, Dong Li, Manhua Cui, Peng Jin and Tianmin Xu

    Citation: Journal of Ovarian Research 2020 13:9

    Content type: Research

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  14. With the improvement of bacterial detection, the theory of the sterile female upper reproductive tract has been frequently challenged in recent years. However, thus far, no researchers have used ovaries as stu...

    Authors: Qi Wang, Lanbo Zhao, Lu Han, Guoxing Fu, Xiaoqian Tuo, Sijia Ma, Qing Li, Yiran Wang, Dongxin Liang, Miaomiao Tang, Chao Sun, Qing Wang, Qing Song and Qiling Li

    Citation: Journal of Ovarian Research 2020 13:8

    Content type: Research

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  15. The timing of the first postpartum ovulation is an important factor affecting the timing of estrous resumption in dairy cows. The first postpartum ovulation is delayed in cows producing large amounts of milk w...

    Authors: Eri Furukawa, Tomoyuki Masaki, Kenichiro Sakaguchi, Min Bo, Yojiro Yanagawa, Koichiro Ueda and Masashi Nagano

    Citation: Journal of Ovarian Research 2020 13:7

    Content type: Research

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  16. To evaluate the diagnostic performance of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) for ovarian cancer.

    Authors: Kexin Li, Yuqing Pei, Yue Wu, Yi Guo and Wei Cui

    Citation: Journal of Ovarian Research 2020 13:6

    Content type: Review

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  17. The complex regulatory mechanism involved in ovarian follicular development is not completely understood. Neuronal neuropeptide Y (NPY) is involved in the regulation of feeding behavior, energy homeostasis, an...

    Authors: Yoko Urata, Reza Salehi, Patricia D. A. Lima, Yutaka Osuga and Benjamin K. Tsang

    Citation: Journal of Ovarian Research 2020 13:5

    Content type: Research

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  18. Lipids are an important source for energy production during oocyte maturation. The accumulation of intracellular lipids binds to proteins to form lipid droplets. This may lead to cellular lipotoxicity. The imp...

    Authors: Shira Raviv, Shay Hantisteanu, Shilhav Meisel Sharon, Yuval Atzmon, Mediea Michaeli and Einat Shalom-Paz

    Citation: Journal of Ovarian Research 2020 13:4

    Content type: Research

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  19. The role of lncRNA miR503HG has been investigated in several types of cancer, but its functions in ovarian cancer (OC) is unclear. Analysis of TCGA dataset revealed a 50-fold lower expression level of miR503HG...

    Authors: Ding Zhu, Xueshuang Huang, Fang Liang and Lijing Zhao

    Citation: Journal of Ovarian Research 2020 13:3

    Content type: Research

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  20. Acute myeloid leukemia (AML) in monozygotic twins is a rare event and, until now, only a few cases have been reported. Due to improved oncological treatment and cancer survival rates, quality of life considera...

    Authors: Tanja Burnik Papler, Eda Vrtacnik Bokal and Nina Jančar

    Citation: Journal of Ovarian Research 2020 13:2

    Content type: Case report

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  21. Secondary cytoreductive surgery (SCS) is possible in selected patients with recurrent epithelial ovarian cancer (EOC). The goal of SCS is complete resection, although chemotherapy is always followed. Delayed i...

    Authors: Soo Young Jeong, Chel Hun Choi, Tae Joong Kim, Jeong Won Lee, Byoung-Gie Kim, Duk Soo Bae and Yoo-Young Lee

    Citation: Journal of Ovarian Research 2019 13:1

    Content type: Research

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  22. Ovarian cancer is the most lethal gynaecologic malignancy. Although there are various subtypes of ovarian cancer, high-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer deaths. Chemoresist...

    Authors: Huan Wu, Rongrong Li, Zhiwei Zhang, Huiyang Jiang, Hanlin Ma, Cunzhong Yuan, Chenggong Sun, Yingwei Li and Beihua Kong

    Citation: Journal of Ovarian Research 2019 12:125

    Content type: Research

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  23. Alpha-fetoprotein (AFP) plays a crucial role in the management of malignant ovarian germ cell tumors (MOGCTs) and is an important reference index for chemotherapy termination. However, a high level of AFP can ...

    Authors: Xuan Zong, Jia-Xin Yang and Ying Zhang

    Citation: Journal of Ovarian Research 2019 12:124

    Content type: Case report

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  24. Endometriosis is considered to be the most intractable cause of female infertility. Administering any type of treatment for endometriosis before in vitro fertilization and embryo transfer (IVF-ET) is an import...

    Authors: Hiroshi Tamura, Hiroaki Yoshida, Hiroyuki Kikuchi, Mai Josaki, Yumiko Mihara, Yuichro Shirafuta, Masahiro Shinagawa, Isao Tamura, Toshiaki Taketani, Akihisa Takasaki and Norihiro Sugino

    Citation: Journal of Ovarian Research 2019 12:123

    Content type: Research

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  25. Epithelial ovarian cancer (EOC) is the deadliest female malignancy. The Wnt/β-catenin pathway plays critical roles in regulating embryonic development and physiological processes. This pathway is tightly regul...

    Authors: Vu Hong Loan Nguyen, Rebecca Hough, Stefanie Bernaudo and Chun Peng

    Citation: Journal of Ovarian Research 2019 12:122

    Content type: Review

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  26. Increasing researches have demonstrated the critical functions of MicroRNAs (miRNAs) in the progression of malignant tumors, including ovarian cancer. It was reported that miR-552 was an important oncogene in ...

    Authors: Wenman Zhao, Tao Han, Bao Li, Qianyun Ma, Pinghua Yang and Hengyu Li

    Citation: Journal of Ovarian Research 2019 12:121

    Content type: Research

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  27. Ovarian cancer has the highest ratio of mortality among gynecologic malignancies. Chemotherapy is one of the most common treatment options for ovarian cancer. However, tumor relapse in patients with advanced t...

    Authors: Vahideh Keyvani, Moein Farshchian, Seyed-Alireza Esmaeili, Hadi Yari, Meysam Moghbeli, Seyed-Reza Kazemi Nezhad and Mohammad Reza Abbaszadegan

    Citation: Journal of Ovarian Research 2019 12:120

    Content type: Review

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  28. Ovarian cancer (OC) is a type of gynaecological malignancy with high mortality in females. Serous ovarian cancer (SOC) is a distinct subtype of OC with poor early diagnosis. Given the limitations of traditiona...

    Authors: Zhi-Ying Qi, Fang Wang, Ying-Ying Yue, Xue-Wang Guo, Rui-Meng Guo, Hong-Lin Li and Yan-Ying Xu

    Citation: Journal of Ovarian Research 2019 12:118

    Content type: Research

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  29. Poly (ADP-ribose) polymerase (PARP) inhibitor, is a milestone in treatment of ovarian cancer. However, there is no real world study from China regarding the clinical outcome of the taking PARP inhibitor (PARPi...

    Authors: Jing Ni, Xianzhong Cheng, Rui Zhou, Xia Xu, Wenwen Guo and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2019 12:117

    Content type: Research

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  30. Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individ...

    Authors: Naoko Sasamoto, Ana Babic, Bernard A. Rosner, Renée T. Fortner, Allison F. Vitonis, Hidemi Yamamoto, Raina N. Fichorova, Linda J. Titus, Anne Tjønneland, Louise Hansen, Marina Kvaskoff, Agnès Fournier, Francesca Romana Mancini, Heiner Boeing, Antonia Trichopoulou, Eleni Peppa…

    Citation: Journal of Ovarian Research 2019 12:116

    Content type: Research

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  31. Growing evidence indicates that the tumor biomarker cytokeratin 19 fragment (CYFRA21-1) is significant for a variety of cancers. However, its role in epithelial ovarian cancer (EOC) has rarely been reported. I...

    Authors: Chunjing Jin, Minfeng Yang, Xueqiao Han, Haidan Chu, Yan Zhang, Meihong Lu, Zhonghui Wang, Xinxin Xu, Wenwen Liu, Feng Wang and Shaoqing Ju

    Citation: Journal of Ovarian Research 2019 12:114

    Content type: Research

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  32. Ovarian cancer is the leading cause of gynecological cancer-related mortality. The novel oncogene S100A10 has been reported to be involved in cancer cell proliferation, invasion and metastasis. The role of S10...

    Authors: Lingzhi Wang, Wei Yan, Xukun Li, Zhihua Liu, Tian Tian, Tanxiu Chen, Liang Zou and Zhumei Cui

    Citation: Journal of Ovarian Research 2019 12:113

    Content type: Research

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  33. Ovarian cancer is the leading cause of gynecologic cancer death in the United States despite effective first-line systemic chemotherapy. Cancer stem cells (CSCs) retain the ability to self-renew and proliferat...

    Authors: Elizabeth V. Connor, Caner Saygin, Chad Braley, Andrew C. Wiechert, Sheelarani Karunanithi, Katie Crean-Tate, Fadi W. Abdul-Karim, Chad M. Michener, Peter G. Rose, Justin D. Lathia and Ofer Reizes

    Citation: Journal of Ovarian Research 2019 12:112

    Content type: Research

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  34. Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases. At present, the cause of the disease is not fully understood, but many studies have shown that PCOS is associated with genetic and...

    Authors: Faezeh Tadaion Far, Shahideh Jahanian Sadatmahalleh, Saeideh Ziaei and Anoshirvan Kazemnejad

    Citation: Journal of Ovarian Research 2019 12:111

    Content type: Research

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  35. Ovarian cancer (OC) is the deadliest cause in the gynecological malignancies. Most OC patients are diagnosed in advanced stages with less than 40% of women cured. However, the possible mechanism underlying tum...

    Authors: Jiayu Shen, Shuqian Yu, Xiwen Sun, Meichen Yin, Jing Fei and Jianwei Zhou

    Citation: Journal of Ovarian Research 2019 12:110

    Content type: Research

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  36. Polycystic ovary syndrome (PCOS) is a complex endocrine disorder and regarded as the leading cause of anovulatory infertility. PCOS is characterized by reproductive dysfunction and metabolic disorders. Baicali...

    Authors: Wei Wang, Jiahua Zheng, Na Cui, Lei Jiang, Han Zhou, Dan Zhang and Guimin Hao

    Citation: Journal of Ovarian Research 2019 12:109

    Content type: Research

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  37. Ovarian cancer during pregnancy is relatively rare and treatment strategies are inexperienced in surgery and chemotherapy. Multidisciplinary management of advanced epithelial ovarian cancer in pregnant patient...

    Authors: Tianmin Xu, Liang Wang, Yan Jia, Zanhui Jia, Zhuo Li, Shaohai Cui and Manhua Cui

    Citation: Journal of Ovarian Research 2019 12:108

    Content type: Case report

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  38. Cisplatin-based chemotherapy is the first-line treatment for ovarian cancer. However, acquired resistance to cisplatin treatment often occurs in epithelial ovarian cancer, and effective and practical methods f...

    Authors: Bo Zhou, Meng Xia, Bin Wang, Niresh Thapa, Lijuan Gan, Chaoyang Sun, Ensong Guo, Jia Huang, Yulan Lu and Hongbin Cai

    Citation: Journal of Ovarian Research 2019 12:107

    Content type: Research

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  39. Ovarian carcinoma (OC) is a common cause of death among women with gynecological cancer. MicroRNAs (miRNAs) are believed to have vital roles in tumorigenesis of OC. Although miRNAs are broadly recognized in OC...

    Authors: Yaowei Li and Li Li

    Citation: Journal of Ovarian Research 2019 12:106

    Content type: Research

    Published on:

  40. Epithelial ovarian cancer (EOC) remains the most lethal gynecological cancer in developed countries, indicating the need for further research. Although current cancer models prove useful, they have major limit...

    Authors: Sander Dumont, Ziga Jan, Ruben Heremans, Toon Van Gorp, Ignace Vergote and Dirk Timmerman

    Citation: Journal of Ovarian Research 2019 12:105

    Content type: Review

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  41. Young girls before menarche or menstruating adolescent women may experience long-term drug-resistant chronic pelvic pain, as well as other symptoms associated with pelvic mass. In such cases, it is of great im...

    Authors: Krzysztof Gałczyński, Maciej Jóźwik, Dorota Lewkowicz, Anna Semczuk-Sikora and Andrzej Semczuk

    Citation: Journal of Ovarian Research 2019 12:104

    Content type: Review

    Published on:

  42. Epithelial ovarian cancer (EOC) is usually diagnosed late at an advanced stage. Though EOC initially responds to treatment, the recurrence rate is pretty high. The efficacy of different targeted therapies redu...

    Authors: Sudeep Gupta, Shona Nag, Shyam Aggarwal, Amit Rauthan and Narayanankutty Warrier

    Citation: Journal of Ovarian Research 2019 12:103

    Content type: Review

    Published on:

  43. Breast cancer is the most common cancer in young women. Fortunately current survival rates of BC are significant which makes future fertility very important for quality of life of BC survivors. Chemotherapy ca...

    Authors: Cristina Silva, Ana Cristina Ribeiro Rama, Sérgio Reis Soares, Mariana Moura-Ramos and Teresa Almeida-Santos

    Citation: Journal of Ovarian Research 2019 12:102

    Content type: Research

    Published on:

  44. Ovarian carcinoma is a lethal gynecological malignancy. Women with ovarian cancer (OC) are highly recurrent and typically diagnosed at late stage. Ten-eleven translocation protein 3 (TET3) belongs to the famil...

    Authors: Tiefeng Cao, Wenwei Pan, Xiaoli Sun and Huimin Shen

    Citation: Journal of Ovarian Research 2019 12:101

    Content type: Review

    Published on:

  45. Ovarian cancer is the most common gynecological malignancy that causes cancer-related deaths in women today; this being the case, developing an understanding of ovarian cancer has become one of the major drivi...

    Authors: Yingyu Dou, Xiaoyan Jiang, Hui Xie, Junyu He and Songshu Xiao

    Citation: Journal of Ovarian Research 2019 12:99

    Content type: Review

    Published on:

  46. Endometriosis patients undergoing in vitro fertilization-embryo transfer (IVF-ET) treatment suffer from lower success rates. The success of IVF-ET is related to the receptivity of the uterus and the quality of...

    Authors: Yu Liang, Xiaokui Yang, Yonglian Lan, Lingling Lei, Ying Li and Shuyu Wang

    Citation: Journal of Ovarian Research 2019 12:98

    Content type: Research

    Published on:

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