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  1. It is well described that circulating progesterone (P4) plays a key role in several reproductive events such as oocyte maturation. However, during diestrus, when circulating P4 is at the highest concentrations...

    Authors: Paola Maria da Silva Rosa, Alessandra Bridi, Giuliana de Ávila Ferronato, Cibele Maria Prado, Natália Marins Bastos, Juliano Rodrigues Sangalli, Flávio Vieira Meirelles, Felipe Perecin and Juliano Coelho da Silveira
    Citation: Journal of Ovarian Research 2024 17:65
  2. Ovarian cancer (OC) is a severe gynecological malignancy with significant diagnostic and therapeutic challenges. The discovery of reliable cancer biomarkers can be used to adjust diagnosis and improve patient ...

    Authors: Shihao Hong, Ni Fu, Shanliang Sang, Xudong Ma, Fangying Sun and Xiao Zhang
    Citation: Journal of Ovarian Research 2024 17:64
  3. Artificial Intelligence entails the application of computer algorithms to the huge and heterogeneous amount of morphodynamic data produced by Time-Lapse Technology. In this context, Machine Learning (ML) metho...

    Authors: S. Canosa, N. Licheri, L. Bergandi, G. Gennarelli, C. Paschero, M. Beccuti, D. Cimadomo, G. Coticchio, L. Rienzi, C. Benedetto, F. Cordero and A. Revelli
    Citation: Journal of Ovarian Research 2024 17:63
  4. Premature ovarian failure (POF) is a devastating condition for women under 40 years old. Chemotherapy, especially the use of cisplatin, has been demonstrated to promote the apoptosis of granulosa cells in prim...

    Authors: Rongli Wang, Feiyan Cheng and Xinyuan Yang
    Citation: Journal of Ovarian Research 2024 17:62
  5. Lymph node metastasis (LNM) is a major factor contributing to the high mortality rate of ovarian cancer, making the treatment of this disease challenging. However, the molecular mechanism underlying LNM in ova...

    Authors: Jiajia Li, Yihua Sun, Xiuling Zhi, Yating Sun, Zulimire Abudousalamu, Qianhan Lin, Bin Li, Liangqing Yao and Mo Chen
    Citation: Journal of Ovarian Research 2024 17:61
  6. Follitropin delta is a novel recombinant follicle stimulating hormone preparation uniquely expressed in a human fetal retinal cell line by recombinant DNA technology. To date, no systematic review was availabl...

    Authors: Stefano Palomba, Donatella Caserta, Paolo Emanuele Levi-Setti and Andrea Busnelli
    Citation: Journal of Ovarian Research 2024 17:60
  7. To investigate the clinical and magnetic resonance imaging (MRI) features for preoperatively discriminating  primary ovarian mucinous malignant tumors (POMTs) and metastatic mucinous carcinomas involving the o...

    Authors: Song-Qi Cai, Min-Rong Wu, Xiao-Liang Ma, Jing-Jing Lu, Jin-Wei Qiang, Yin-Yin Guan, Meng-Su Zeng and Jian-Jun Zhou
    Citation: Journal of Ovarian Research 2024 17:59
  8. Tumors are highly heterogeneous, and within their parenchyma, a small population of tumor-stem cells possessing differentiation potential, high oncogenicity, and self-renewal capabilities exists. These cells a...

    Authors: Guangwei Wang, Xiaofei Liu, Yue You, Silei Chen, Xiaohan Chang and Qing Yang
    Citation: Journal of Ovarian Research 2024 17:58
  9. Mesonephric-like adenocarcinoma is a new class of rare subtypes of the female reproductive system. Its clinical symptoms are similar to other types of ovarian tumors. The diagnosis is based on pathological and...

    Authors: Yun Yang, Mengru Zhao, Qiuchen Jia, Huimin Tang, Tingwei Xing, Yang Li, Bin Tang, Lin Xu, Weiwei Wei, Hong Zheng, Ruxia Shi, Bairong Xia and Jiming Chen
    Citation: Journal of Ovarian Research 2024 17:57
  10. The efficacy of subsequent therapy after poly-ADP-ribose polymerase (PARP) inhibitor maintenance treatment has raised concerns. Retrospective studies show worse outcomes for platinum-based chemotherapy after p...

    Authors: Nan Zhang, Hong Zheng, Yunong Gao, Tong Shu, Hongguo Wang and Yan Cai
    Citation: Journal of Ovarian Research 2024 17:55
  11. Oocytes of large animal species isolated from small ovarian follicles (< 2 mm) are less competent to support early embryonic development after in vitro maturation and fertilization than their counterparts isol...

    Authors: Alexandra Rosenbaum Bartková, Lucie Němcová, Veronika Kinterová, Dominika Radová, František Strejček, Tereza Toralová, Jozef Laurinčík and Radek Procházka
    Citation: Journal of Ovarian Research 2024 17:54
  12. Ovarian cancer is the eighth leading cause of cancer-related death among women, characterized by late diagnosis and a high relapse rate. In randomized controlled trials, we aimed to evaluate the efficacy and s...

    Authors: István Baradács, Brigitta Teutsch, Alex Váradi, Alexandra Bilá, Ádám Vincze, Péter Hegyi, Tamás Fazekas, Balázs Komoróczy, Péter Nyirády, Nándor Ács, Ferenc Bánhidy and Balázs Lintner
    Citation: Journal of Ovarian Research 2024 17:53
  13. Despite receiving first-line treatment, ovarian cancer patients continue to experience a high rate of recurrence; nearly all women with ovarian cancer develop chemoresistance and succumb to the disease. In thi...

    Authors: Biyao Jiang, Songshu Xiao, Shan Zhang and Fang Xiao
    Citation: Journal of Ovarian Research 2024 17:52
  14. Individual patients with ovarian cancer show remarkably different prognosis. Present prognostic models for ovarian cancer mainly focus on clinico-pathological parameters, so quantifiable prognostic markers at ...

    Authors: Hao Wang, Yin-hai Xu and Yi Guo
    Citation: Journal of Ovarian Research 2024 17:50
  15. Ovarian cancer is a significant challenge in women's health due to the lack of effective screening and diagnostic methods, often leading to late detection and the highest mortality rate among all gynecologic t...

    Authors: Ning Li, Xingmei Jiang, Qingyu Zhang, Yongmei Huang, Jinbin Wei, Haitao Zhang and Hui Luo
    Citation: Journal of Ovarian Research 2024 17:49
  16. Despite advances in medical imaging technology, the accurate preoperative prediction of lymph node status remains challenging in ovarian cancer. This retrospective study aimed to investigate the feasibility of...

    Authors: Yue Qi, Jinchi Liu, Xinyue Wang, Yuqing Zhang, Zhixun Li, Xinyu Qi and Ying Huang
    Citation: Journal of Ovarian Research 2024 17:48
  17. Evidence from the Istanbul consensus workshop suggests correlations between morphological parameters and embryo developments. 8-cell embryos are the best blastomere stage on day 3. No good quality evidence exi...

    Authors: Haijing Zhao, Keer Gan, Xiaohui Ji, Lingyan Zheng, Songbang Ou, Mei Mei, Qingxue Zhang, Hui Chen, Ping Yuan and Wenjun Wang
    Citation: Journal of Ovarian Research 2024 17:47
  18. Polycystic ovary syndrome (PCOS) is one of the most complex endocrine disorders in women of reproductive age. Abnormal proliferation of granulosa cells (GCs) is an important cause of PCOS. This study aimed to ...

    Authors: Jingyu Liu, Jie Li, Xin Wu, Mei Zhang, Guijun Yan, Haixiang Sun and Dong Li
    Citation: Journal of Ovarian Research 2024 17:44
  19. Polycystic ovary syndrome (PCOS) is a gynecological endocrine disease and could be considered a metabolic disease because it is often accompanied by obesity and insulin resistance. Brown adipose tissue (BAT) t...

    Authors: Yan Yan, Fangfang Di, Ruoxi Zhang, Liwen Song, Runjie Zhang and Jin Qiu
    Citation: Journal of Ovarian Research 2024 17:43
  20. To investigate the effects of metformin (MET) monotherapy and pioglitazone plus MET (PIOMET) therapy on gonadal and metabolic profiles in normal-weight women with polycystic ovary syndrome (PCOS).

    Authors: Han Zhao, Jiaqi Zhang, Chuan Xing, Xiangyi Cheng and Bing He
    Citation: Journal of Ovarian Research 2024 17:42
  21. Mucin 16 (MUC16) overexpression is linked with cancer progression, metastasis, and therapy resistance in high grade serous ovarian cancer and other malignancies. The cleavage of MUC16 forms independent bimodul...

    Authors: Kwangkook Lee, Kay Perry, Mengyao Xu, Irva Veillard, Raj Kumar, Thapi Dharma Rao, Bo R Rueda, David R Spriggs and Oladapo O Yeku
    Citation: Journal of Ovarian Research 2024 17:41
  22. Poor ovarian response (POR) is a big challenge for in vitro fertilization. The traditional Chinese medicine, Cai’s Prescription of Tonifying Kidney and Strengthening Vitals (Cai’s Prescription) has yielded sat...

    Authors: Zheng Wang, Denghao Liu, Yonghong Nie and Qinhua Zhang
    Citation: Journal of Ovarian Research 2024 17:40
  23. PCOS is a widespread disease that primarily caused in-pregnancy in pregnant-age women. Normoandrogen (NA) and Hyperandrogen (HA) PCOS are distinct subtypes of PCOS, while bio-markers and expression patterns fo...

    Authors: Wensu Liu, Tianyu Tang, Jianwei Feng, Chunyu Wang, Lin Lin, Shengli Wang, Kai Zeng, Renlong Zou, Zeyu Yang and Yue Zhao
    Citation: Journal of Ovarian Research 2024 17:38
  24. The present study aimed to explore the maternal and perinatal risks in cases of monozygotic twins (MZT) following frozen-thawed embryo transfer (FET).

    Authors: Jing Lin, Kai Zhang, Fenglu Wu, Bian Wang, Weiran Chai, Qianqian Zhu, Jialyu Huang and Jiaying Lin
    Citation: Journal of Ovarian Research 2024 17:36
  25. PAQR7 plays a key role in cell apoptosis as a progesterone membrane receptor. The physiological mechanism of PAQR7 in ovarian function and its anti-apoptotic action in mammals remain poorly understood.

    Authors: Jia Li, Yiting Liu, Jinxia He, Zixuan Wu, Fang Wang, Jian Huang, Liping Zheng and Tao Luo
    Citation: Journal of Ovarian Research 2024 17:35
  26. Ovarian cancer (OC) is the most lethal gynecologic malignant tumour. The mechanism promoting OC initiation and progression remains unclear. SET domain bifurcated histone lysine methyltransferase 1(SETDB1) acts...

    Authors: Hongjuan Yang, Lei Sui, Cuicui Cai, Huijun Chu and Yuchao Diao
    Citation: Journal of Ovarian Research 2024 17:34
  27. The etiology of premature ovarian insufficiency, that is, the loss of ovarian activity before 40 years of age, is complex. Studies suggest that genetic factors are involved in 20–25% of cases. The aim of this ...

    Authors: Panpan Long, Le Wang, Hangjing Tan, Ruping Quan, Zihao Hu, Minghua Zeng, Ziheng Deng, Hualin Huang, Jonathan Greenbaum, Hongwen Deng and Hongmei Xiao
    Citation: Journal of Ovarian Research 2024 17:32
  28. Investigating the underlying molecular mechanisms responsible for endometrial dysfunction in women with PCOS is essential, particularly focusing on the role of hyperinsulinemia.

    Authors: Nan-Xing Jiang, Wei-Jie Zhao, Hao-Ran Shen, Dan-feng Du and Xue-Lian Li
    Citation: Journal of Ovarian Research 2024 17:31
  29. Ovarian cancer is the most lethal gynecologic neoplasm, and most patients experience recurrence and chemoresistance. Even the promising immunotherapy showed limited efficacy in ovarian cancer, probably due to ...

    Authors: Ming Du, Qingqing Cai, Jiaan Sun, Mingxing Zhang, Shuo Zhang, Xiaoxia Liu, Mengyu Zhang and Xiaoyan Zhang
    Citation: Journal of Ovarian Research 2024 17:30
  30. Polycystic ovary syndrome (PCOS) is a frequent and complicated endocrine disease that remains a major reason for infertility. Bushenhuoluo Decotion (BSHLD) has been validated to exhibit curative effects on PCO...

    Authors: Qun Huang, Yuanbin Li, Zhuang Chen, Huiping Ou, Yanjiao Tan and Hui Lin
    Citation: Journal of Ovarian Research 2024 17:29
  31. Polycystic Ovary Syndrome (PCOS) affects a significant proportion of human females worldwide and is characterized by hormonal, metabolic, and reproductive dysfunctions, including infertility, irregular menstru...

    Authors: Fatima Muccee, Naeem Mahmood Ashraf, Suhail Razak, Tayyaba Afsar, Nadia Hussain, Fohad Mabood Husain and Huma Shafique
    Citation: Journal of Ovarian Research 2024 17:27
  32. Ovarian cancer (OC) is one of the most common gynecological tumors with high morbidity and mortality. Altered serum N-glycome has been observed in many diseases, while the association between serum protein N-glyc...

    Authors: Si Liu, Chang Tu, Haobo Zhang, Hanhui Huang, Yuanyuan Liu, Yi Wang, Liming Cheng, Bi-Feng Liu, Kang Ning and Xin Liu
    Citation: Journal of Ovarian Research 2024 17:26
  33. Bushen Tiaoxue Granules (BTG) is an empirical Chinese herbal formula that has been used for the treatment of subfertility. The protective effect of BTG on controlled ovarian hyperstimulation (COH)-induced impa...

    Authors: Jia-Cheng Zhang, Hao-Lin Zhang, Xi-Yan Xin, Yu-Tian Zhu, Xin Mao, Hang-Qi Hu, Yu-Xin Jin, Rui-Wen Fan, Xiao-Hui Zhang, Yang Ye and Dong Li
    Citation: Journal of Ovarian Research 2024 17:25
  34. Premature ovarian failure (POF) is a leading cause of women’s infertility without effective treatment. The purpose of this study was to investigate the protective effects of Luffa cylindrica fermentation liquid (...

    Authors: Yueying Feng, Wei Zhang, Xiaowei Xu, Wanzhen Wang, Yuanyuan Xu, Mengqi Wang, Jinfeng Zhang, Hengyi Xu and Fen Fu
    Citation: Journal of Ovarian Research 2024 17:24
  35. In fully grown oocytes, the genome is considered to be globally transcriptionally silenced. However, this conclusion is primarily derived from the results obtained through immunofluorescence staining or inferr...

    Authors: Huiqing An, Xiuwan Wang, Jiashuo Li, Hongzheng Sun, Shuai Zhu, Juan Ge, Longsen Han, Bin Shen and Qiang Wang
    Citation: Journal of Ovarian Research 2024 17:23
  36. The mechanisms and risk factors underlying ovarian cancer (OC) remain under investigation, making the identification of new prognostic biomarkers and improved predictive factors critically important. Recently,...

    Authors: Shaoxuan Liu, Danni Ding, Fangyuan Liu, Ying Guo, Liangzhen Xie and Feng-Juan Han
    Citation: Journal of Ovarian Research 2024 17:22
  37. Women have polycystic ovarian syndrome (PCOS) at higher rates than any other endocrine condition with an average incidence rate of 6 to 8%. Acne is an immune mediate common condition frequently affecting adole...

    Authors: Heba I. Elnagar, Osama A. Hashem, Hany O. Aboelwafa, Ehab Elhelw and Mohamed L. Elsaie
    Citation: Journal of Ovarian Research 2024 17:21
  38. Bisphenol A (BPA), an endocrine disrupting chemical with weak estrogenic and anti-androgenic activity, is widely present in various environmental media and organisms. It has certain reproductive toxicity and c...

    Authors: Chen Wang, Chaofan He, Shumin Xu, Yuanyuan Gao, Kaixian Wang, Meng Liang and Ke Hu
    Citation: Journal of Ovarian Research 2024 17:20
  39. MUC16 is a heavily glycosylated cell surface mucin cleaved in the tumor microenvironment to shed CA125. CA125 is a serum biomarker expressed by > 95% of non-mucinous advanced stage epithelial ovarian cancers. ...

    Authors: Hsin-Fang Tu, Margaret Wong, Ssu-Hsueh Tseng, Nattha Ingavat, Pola Olczak, Kin Israel Notarte, Chien-fu Hung and Richard B.S. Roden
    Citation: Journal of Ovarian Research 2024 17:19
  40. The ovarian environment of premature ovarian insufficiency (POI) patients exhibits immune dysregulation, which leads to excessive secretion of numerous proinflammatory cytokines that affect ovarian function. A...

    Authors: Bingbing Hu, Xiushuang Zheng and Wei Zhang
    Citation: Journal of Ovarian Research 2024 17:18
  41. Polycystic ovarian syndrome (PCOS) is a genetically complex disorder that involves the interplay of multiple genes and environmental factors. It is characterized by anovulation and irregular menses and is asso...

    Authors: Teodor T. Postolache, Qamar M. Al Tinawi and Claudia Gragnoli
    Citation: Journal of Ovarian Research 2024 17:17

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