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  1. Content type: Review

    The use of patient reported outcome measures (PROMs) has increased during the past decade, and the focus on how to use them has resulted in a more proactive application. Studies have shown that proactive use o...

    Authors: Anette Stolberg Kargo, Angela Coulter, Pernille Tine Jensen and Karina Dahl Steffensen

    Citation: Journal of Ovarian Research 2019 12:63

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  2. Content type: Research

    All-trans retinoic acid (ATRA) is currently being used to treat hematological malignancies, given the ability to inhibit cell proliferation. This effect seems to be related to epigenetic changes of the TERT (Telo...

    Authors: Lorena Losi, Angela Lauriola, Erica Tazzioli, Gaia Gozzi, Letizia Scurani, Domenico D’Arca and Jean Benhattar

    Citation: Journal of Ovarian Research 2019 12:62

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  3. Content type: Research

    Premature ovarian insufficiency (POI) leads to early loss of ovarian function in women aged < 40 years and is highly heterogeneous in etiology. The genetic etiology of this disorder remains unknown in most wom...

    Authors: Jing Zhe, Shiling Chen, Xin Chen, Yudong Liu, Ying Li, Xingyu Zhou and Jun Zhang

    Citation: Journal of Ovarian Research 2019 12:61

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  4. Content type: Research

    To investigate whether miR-203a-3p can regulate the biological behaviors of ovarian cancer cells by targeting ATM to affect the Akt/GSK-3β/Snail signaling pathway.

    Authors: Hong-Yun Liu, Yu-Ying Zhang, Bao-Lian Zhu, Fu-Zhong Feng, Hai-Tang Zhang, Hua Yan and Bin Zhou

    Citation: Journal of Ovarian Research 2019 12:60

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  5. Content type: Research

    To determine whether magnetic resonance (MR) imaging features combined with apparent diffusion coefficient (ADC) values could be used as a tool for categorizing ovarian epithelial cancer (OEC) and predicting surv...

    Authors: Guofu Zhang, Weigen Yao, Taotao Sun, Xuefen Liu, Peng Zhang, Jun Jin, Yu Bai, Keqin Hua and He Zhang

    Citation: Journal of Ovarian Research 2019 12:59

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  6. Content type: Research

    In order to preserve fertility in young women with disseminated cancer, e.g. leukemia, an approach that has been suggested is to retransplant isolated small follicles within an ovarian matrix free from maligna...

    Authors: Ahmed Baker Alshaikh, Arvind Manikantan Padma, Matilda Dehlin, Randa Akouri, Min Jong Song, Mats Brännström and Mats Hellström

    Citation: Journal of Ovarian Research 2019 12:58

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  7. Content type: Research

    PD-L1 expression levels determined by immunostaining are known to be related to the survival rate and prognosis of patients with various types of cancers, as well as to the therapeutic response to immune check...

    Authors: Ki Hyung Kim, Kyung Un Choi, Ahrong Kim, So Jung Lee, Jung Hee Lee, Dong Soo Suh, Byung-su Kwon and Chungsu Hwang

    Citation: Journal of Ovarian Research 2019 12:56

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  8. Content type: Review

    Ovarian cancer is the main cause of death among all reproductive cancers in females. In 2018, ovarian cancer was the seventh most common cancer of women entire the world. A wide variety of molecular and geneti...

    Authors: Rana Shafabakhsh and Zatollah Asemi

    Citation: Journal of Ovarian Research 2019 12:55

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  9. Content type: Research

    The incidence of intraepithelial neoplasia in the fallopian tubes of women over 40 years of age who had undergone elective hysterectomy was assessed at the Aguascalientes Women’s Hospital.

    Authors: Antonio Gabriel Briseño Campos, Antonio Cruz Rodríguez, Martha Olivia García Perales, Francisco Javier Serna Vela, Diana Gabriela Camarillo Elizalde and María del Consuelo Robles Martínez

    Citation: Journal of Ovarian Research 2019 12:54

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  10. Content type: Research

    To explore the mechanisms of ovarian aging, we performed overall analysis on the age-related alterations of gene expression profiles in mouse germinal vesicle (GV) stage oocytes by means of single-cell RNA-seq...

    Authors: Tao Zhang, Qingsong Xi, Dan Wang, Jingjing Li, Meng Wang, Dan Li, Lixia Zhu and Lei Jin

    Citation: Journal of Ovarian Research 2019 12:53

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  11. Content type: Case report

    The ovary is an important organ of the female reproductive system, which produces oocytes and secretes reproductive hormones. Ovaries have complex dual blood supplies with their blood supply being the core com...

    Authors: Jun Ying, Jiawen Feng, Jinghui Hu, Shuo Wang, Peilin Han, Yujie Huang, Wei Zhao and Jianhua Qian

    Citation: Journal of Ovarian Research 2019 12:52

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  12. Content type: Review

    Prognostic biomarkers are highly needed to properly manage patients with cancer and improve their clinical courses. The relationship between lymphocyte-to-monocyte ratio (LMR) at diagnosis and ovarian cancer p...

    Authors: Jun Gong, Hui Jiang, Chang Shu, Mei-qin Hu, Yan Huang, Qin Liu and Rong-feng Li

    Citation: Journal of Ovarian Research 2019 12:51

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  13. Content type: Research

    The management of Serous Tubal Intraepithelial Carcinoma (STIC) found at the time of Risk-Reducing Salpingo-Oophorectomy (RRSO) remains unclear. We set out to analyse the incidence of peritoneal carcinomas dev...

    Authors: P. I. Stanciu, T. E. J. Ind, D. P. J. Barton, J. B. Butler, K. M. Vroobel, A. D. Attygalle and M. A. E. Nobbenhuis

    Citation: Journal of Ovarian Research 2019 12:50

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  14. Content type: Research

    We have previously shown that a whole flaxseed supplemented diet decreased the onset and severity of ovarian cancer in the laying hen, the only known animal model of spontaneous ovarian cancer. Flaxseed is ric...

    Authors: Purab Pal, Karen Hales, Jim Petrik and Dale Buchanan Hales

    Citation: Journal of Ovarian Research 2019 12:49

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  15. Content type: Research

    The antral follicle count is a marker of ovarian reserve. Follicular Output RaTe (FORT) evaluates the proportion of follicles responsive to exogenous follicle stimulating hormone (FSH) during controlled ovaria...

    Authors: Camila Bessow, Rafaela Donato, Tatiane de Souza, Rita Chapon, Vanessa Genro and João Sabino Cunha-Filho

    Citation: Journal of Ovarian Research 2019 12:48

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  16. Content type: Research

    To study the quality of our human ovarian tissue cryopreservation technique as performed in the first official "International Fertility Protection Centre" in China in patients with certain cancer types using a...

    Authors: Xiangyan Ruan, Yamei Cui, Juan Du, Jing Jin, Muqing Gu, Suwen Chen and Alfred O. Mueck

    Citation: Journal of Ovarian Research 2019 12:46

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  17. Content type: Research

    While tumor suppressor p53 functions primarily as a transcription factor in the nucleus, cellular stress can cause p53 to translocate to the mitochondria and directly trigger a rapid apoptotic response. We hav...

    Authors: Phong Lu, Erica R. Vander Mause, Katherine E. Redd Bowman, Sarah M. Brown, Lisa Ahne and Carol S. Lim

    Citation: Journal of Ovarian Research 2019 12:45

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  18. Content type: Research

    To detected both pregnancy and oncologic outcomes early stage low grade epithelial ovarian cancer (EOC) in one tertiary hospital of China.

    Authors: Jie Yin, Yongxue Wang, Ying Shan, Yan Li, Ying Jin and Lingya Pan

    Citation: Journal of Ovarian Research 2019 12:44

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  19. Content type: Research

    Chemokines are involved in the homing of various cancer cells, including those of ovarian cancer (OvCa), to distant organs. They may also promote or inhibit cancer progression and metastasis. Hypoxia, a common...

    Authors: Santosh Kumar Singh, Manoj Kumar Mishra and Rajesh Singh

    Citation: Journal of Ovarian Research 2019 12:42

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  20. Content type: Research

    Ovarian cancer is a common gynaecological cancer with a poor prognosis that poses a serious threat to human life and health. It is essential to explore the possible prognostic biomarkers of ovarian cancer. As ...

    Authors: Ziqian Sun, Liang Sun, Miao He, Ying Pang, Zhaoying Yang and Junrong Wang

    Citation: Journal of Ovarian Research 2019 12:41

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  21. Content type: Research

    Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder characterized by obesity, hyperandrogenism, and insulin resistance (IR). MicroRNAs (miRNAs) are small noncoding RNA associated with ...

    Authors: Nearmeen M. Rashad, Marwa Abdel-Monem Ateya, Yasser S. Saraya, Walid Mohamed Elnagar, Khaled Fathy Helal, Mohamed El-Bakry Lashin, Amr Ahmed Abdelrhman, Ayman E. Alil and Mohammed S. Yousef

    Citation: Journal of Ovarian Research 2019 12:39

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  22. Content type: Research

    Despite years of research, the treatment options and mortality rate for ovarian cancer remain relatively stagnant. Resistance to chemotherapy and high heterogeneity in mutations contribute to ovarian cancer’s ...

    Authors: Katherine Redd Bowman, Ji Hoon Kim and Carol S. Lim

    Citation: Journal of Ovarian Research 2019 12:38

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  23. Content type: Research

    Epithelial ovarian cancer has the highest fatality rate of all gynecologic malignancies. Although the majority of patients achieve complete clinical response after initial cytoreductive surgery and platinum-ba...

    Authors: Samantha Cohen, Melissa Schwartz, Peter Dottino and Ann Marie Beddoe

    Citation: Journal of Ovarian Research 2019 12:36

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  24. Content type: Research

    Ovarian cancer (OC) is the highest frequent malignant gynecologic tumor with very complicated pathogenesis. The purpose of the present academic work was to identify significant genes with poor outcome and thei...

    Authors: Hao Feng, Zhong-Yi Gu, Qin Li, Qiong-Hua Liu, Xiao-Yu Yang and Jun-Jie Zhang

    Citation: Journal of Ovarian Research 2019 12:35

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  25. Content type: Review

    Ral interacting protein of 76 kDa (RLIP76) is multifunctional protein localized and distributed in the plasma membrane, cytosol, and nucleus of the cell. In tumorigenesis, RLIP76 emerges as a common feature fo...

    Authors: Dody Houston Billhaq and Seunghyung Lee

    Citation: Journal of Ovarian Research 2019 12:34

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  26. Content type: Review

    Previous studies about the prognostic value of the HIPEC have yielded controversial results. Therefore, this study aims to assess the impact of HIPEC on patients with ovarian cancer.

    Authors: Guyu Zhang, Yimin Zhu, Chongdong Liu, Guangming Chao, Ran Cui and Zhenyu Zhang

    Citation: Journal of Ovarian Research 2019 12:33

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  27. Content type: Case report

    Ovarian carcinosarcoma, which contains sarcomatous and carcinomatous components, is a very rare tumor. The carcinomatous component is often adenocarcinoma, and squamous cell carcinoma is extremely rare. We her...

    Authors: Atsushi Daimon, Satoe Fujiwara, Yoshimichi Tanaka, Tomohito Tanaka and Masahide Ohmichi

    Citation: Journal of Ovarian Research 2019 12:32

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  28. Content type: Research

    Hyperandrogenism is one of the cardinal symptoms in polycystic ovary syndrome and plays a key role in the pathogenesis of polycystic ovary syndrome. However, the precise effects and mechanisms of excess androg...

    Authors: Yuya Fujibe, Tsuyoshi Baba, Sachiko Nagao, Sayaka Adachi, Keiko Ikeda, Miyuki Morishita, Yoshika Kuno, Masahiro Suzuki, Masahito Mizuuchi, Hiroyuki Honnma, Toshiaki Endo and Tsuyoshi Saito

    Citation: Journal of Ovarian Research 2019 12:31

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  29. Content type: Research

    Increased activity of the chaperones Hsp70 and Hsp90 is a common feature of solid tumours. Translocase of the outer mitochondrial membrane 34 (Tomm34) is a cochaperone of both Hsp70 and Hsp90 that was found to...

    Authors: Petr Muller, Philip J. Coates, Rudolf Nenutil, Filip Trcka, Roman Hrstka, Josef Chovanec, Veronika Brychtova and Borivoj Vojtesek

    Citation: Journal of Ovarian Research 2019 12:30

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  30. Content type: Review

    Ovarian cancer is the 5th leading cause of death for women with cancer worldwide. In more than 70% of cases, it is only diagnosed at an advanced stage. Our study aims to give an update on the biological marker...

    Authors: Vincent Dochez, Hélène Caillon, Edouard Vaucel, Jérôme Dimet, Norbert Winer and Guillaume Ducarme

    Citation: Journal of Ovarian Research 2019 12:28

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  31. Content type: Research

    To analyze the clinicopathological characteristics of subsequent pelvic masses after hysterectomy for benign diseases, and to compare the masses following hysterectomy with or without simultaneous bilateral sa...

    Authors: Xiaopei Chao, Xiaoxia Wang, Yu Xiao, Mingliang Ji, Shu Wang, Honghui Shi, Qingbo Fan, Lan Zhu, Jinhua Leng, Dawei Sun and Jinghe Lang

    Citation: Journal of Ovarian Research 2019 12:27

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  32. Content type: Research

    Polycystic ovarian syndrome (PCOS) is a highly variable syndrome and one of the most common female endocrine disorders. Although the association inositols-glucomannan may represent a good therapeutic strategy ...

    Authors: Jacopo Troisi, Claudia Cinque, Luigi Giugliano, Steven Symes, Sean Richards, David Adair, Pierpaolo Cavallo, Laura Sarno, Giovanni Scala, Maria Caiazza and Maurizio Guida

    Citation: Journal of Ovarian Research 2019 12:25

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  33. Content type: Review

    Ovarian cancer is the primary cause of cancer-associated deaths among gynaecological malignancies. Increasing evidence suggests that microRNAs may be potential biomarkers for the diagnosis and prognosis of can...

    Authors: Xinshuai Wang, Dejiu Kong, Chaokun Wang, Xuezhen Ding, Li Zhang, Mengqi Zhao, Jing Chen, Xiangyun Xu, Xiaochen Hu, Junqiang Yang and Shegan Gao

    Citation: Journal of Ovarian Research 2019 12:24

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  34. Content type: Research

    Low-grade ovarian cancers represent up to 8% of all epithelial ovarian carcinomas (EOCs). Recent studies demonstrated that epithelial-mesenchymal transition (EMT) is crucial for the progression of EOCs. EMT pl...

    Authors: Paweł Sadłecki, Marek Grabiec, Dariusz Grzanka, Jakub Jóźwicki, Paulina Antosik and Małgorzata Walentowicz-Sadłecka

    Citation: Journal of Ovarian Research 2019 12:23

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  35. Content type: Research

    Normal pubertal ovary displays all stages of follicular development and a biased BAX/BCL2 protein ratio in favor of pro-apoptotic BAX protein comparable to the adult ovary. However, adolescents suffering malig...

    Authors: María Itatí Albamonte, Mirta Susana Albamonte, Ricardo M. Bou-Khair, Luis Zuccardi and Alfredo Daniel Vitullo

    Citation: Journal of Ovarian Research 2019 12:22

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  36. Content type: Research

    The cumulus expansion process is one of the LH mediated ovulatory processes. Hyaluronan synthase 2 (HAS2) regulates the synthesis of hyaluronic acid, the main component of the cumulus expansion process. Recent...

    Authors: Yuval Yung, Libby Ophir, Gil M. Yerushalmi, Micha Baum, Ariel Hourvitz and Ettie Maman

    Citation: Journal of Ovarian Research 2019 12:21

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  37. Content type: Research

    Common cancerous histological types associated with endometriosis are clear cell carcinoma (CCC) and endometrioid carcinoma (EC). CCC is regarded as an aggressive, chemoresistant histological subtype. Magnetic...

    Authors: Sachiko Morioka, Ryuji Kawaguchi, Yuki Yamada, Kana Iwai, Chiharu Yoshimoto and Hiroshi Kobayashi

    Citation: Journal of Ovarian Research 2019 12:20

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  38. Content type: Research

    Ovarian cancer (OC) is one of the most malignant gynecological tumors, associated with excess death rate (50–60%) in ovarian cancer patients. Particularly, among newly occurred ovarian cancer patients, 70% of ...

    Authors: Lei Zhang, Min Luo, Hongying Yang, Shaoyan Zhu, Xianliang Cheng and Chen Qing

    Citation: Journal of Ovarian Research 2019 12:19

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  39. Content type: Brief Communication

    Virotherapy represents a promising approach for ovarian cancer. In this regard, conditionally replicative adenovirus (CRAd) has been translated to the context of human clinical trials. Advanced design of CRAds...

    Authors: Rebeca González-Pastor, Ahmad Mohammad Ashshi, Adel Galal El-Shemi, Igor P. Dmitriev, Elena A. Kashentseva, Zhi Hong Lu, S. Peter Goedegebuure, Osvaldo L. Podhajcer and David T. Curiel

    Citation: Journal of Ovarian Research 2019 12:18

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  40. Content type: Research

    Relapsed epithelial ovarian cancer (EOC) is frequently treated with pegylated liposomal doxorubicin (PLD). Unfortunately, most patients do not benefit from treatment. Prediction of response is crucial to optim...

    Authors: Eleonora Ghisoni, Furio Maggiorotto, Fulvio Borella, Gloria Mittica, Sofia Genta, Gaia Giannone, Dionyssios Katsaros, Alberto Sciarrillo, Annamaria Ferrero, Ivana Sarotto, Jessica Erriquez, Maria Flavia Di Renzo, Massimo Aglietta and Giorgio Valabrega

    Citation: Journal of Ovarian Research 2019 12:17

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  41. Content type: Research

    The aim of the present study was to investigate the prognostic significance of preoperative complete blood count inflammatory markers in women operated for invasive Epithelial Ovarian Cancer (EOC).

    Authors: Mehmet Ufuk Ceran, Umit Tasdemir, Eser Colak and Tayfun Güngör

    Citation: Journal of Ovarian Research 2019 12:16

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  42. Content type: Research

    Ovarian cancer is the most lethal of all gynecologic malignancies. The relationship between sexual steroids receptors and ovarian cancer progression has been largely evaluated. The presence of progesterone rec...

    Authors: Enrique Pedernera, María J. Gómora, Flavia Morales-Vásquez, Delia Pérez-Montiel and Carmen Mendez

    Citation: Journal of Ovarian Research 2019 12:15

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  43. Content type: Research

    In ovarian endometriomas (OE), the expression statuses of various steroid hormone receptors are altered compared with their expression statuses in eutopic endometrium (EE). For example, in OE, the expressions ...

    Authors: Ryo Maekawa, Yumiko Mihara, Shun Sato, Maki Okada, Isao Tamura, Masahiro Shinagawa, Yuichiro Shirafuta, Haruka Takagi, Toshiaki Taketani, Hiroshi Tamura and Norihiro Sugino

    Citation: Journal of Ovarian Research 2019 12:14

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