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  1. Ovarian squamous cell carcinoma (SCC) is a rare cancer with possible poor survival, however no direct evidence supports this viewpoint and the independent prognostic factors are controversial. Patients with ov...

    Authors: Cheng Zhang and Tai Ma

    Citation: Journal of Ovarian Research 2020 13:75

    Content type: Research

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  2. The prognostic value and optimal resection outcome related factors of the secondary cytoreduction surgery (SCR) in Platinum-sensitive recurrent ovarian cancer (PSOC) patients were still in doubt. The present r...

    Authors: Hongyuan Gu, Rui Zhou, Jing Ni, Xia Xu, Xianzhong Cheng, Yan Li and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2020 13:70

    Content type: Research

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  3. The aim of this study was to determine whether the treatment with doxycycline before and after oocyte retrieval is as effective as salpingectomy in minimizing the detrimental effect of hydrosalpinx on the outc...

    Authors: Usama M. Fouda, Hesham S. Elshaer, Mohamed A. Youssef and Fatma F. Darweesh

    Citation: Journal of Ovarian Research 2020 13:69

    Content type: Research

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  4. Cervical cancer is considered as an important malignancy among women worldwide. Currently-used treatments of cervical cancer are reported to be cytotoxic for patients. Moreover, these therapies have shown some...

    Authors: Moghaddaseh Jahanshahi, Parisa Maleki Dana, Bita Badehnoosh, Zatollah Asemi, Jamal Hallajzadeh, Mohammad Ali Mansournia, Bahman Yousefi, Bahram Moazzami and Shahla Chaichian

    Citation: Journal of Ovarian Research 2020 13:68

    Content type: Review

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  5. Ovarian cancer is the most fatal gynecologic malignancy worldwide due to its vagueness, delay in diagnosis, recurrence, and drug resistance. Therefore, a new type of ovarian cancer treatment prediction biomark...

    Authors: Ze Li, Yongwang Hou, Meng Zhao, Tianning Li, Yahui Liu, Jiao Chang and Li Ren

    Citation: Journal of Ovarian Research 2020 13:67

    Content type: Research

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  6. Co-administration of letrozole during the first 5 days of ovarian stimulation was suggested to improve IVF outcomes in poor responders. We aimed to determine whether poor/sub-optimal responders might benefit f...

    Authors: Moran Shapira, Raoul Orvieto, Oshrit Lebovitz, Ravit Nahum, Adva Aizer, Aliza Segev-Zahav and Jigal Haas

    Citation: Journal of Ovarian Research 2020 13:66

    Content type: Research

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  7. High-grade serous carcinoma (HGSC) of the ovary is the most common subtype of epithelial ovarian cancer (EOC) and has an overall poor prognosis. There is increasing awareness of the importance of immune cell p...

    Authors: Kyung Un Choi, Ahrong Kim, Jee Yeon Kim, Ki Hyung Kim, Chungsu Hwang, So Jung Lee, Won Young Park, Sejin Jung, Hye Jeong Choi and Kyungbin Kim

    Citation: Journal of Ovarian Research 2020 13:65

    Content type: Research

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  8. Increasing researches have demonstrated the critical functions of circular RNAs (circRNAs) in the progression of malignant tumors, including ovarian cancer. In this study, we aim to investigate abnormally expr...

    Authors: Nan Zhang, Yue Jin, Qiubo Hu, Shanshan Cheng, Chao Wang, Zhiyou Yang and Yu Wang

    Citation: Journal of Ovarian Research 2020 13:64

    Content type: Research

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  9. Granulosa cells (GCs) are somatic cells surrounding oocytes within follicles and are essential for folliculogenesis. Pathological changes in GCs are found in several ovarian disorders. Recent reports have indi...

    Authors: Jiajie Tu, Yu Chen, Zhe Li, Huan Yang, He Chen and Zhiying Yu

    Citation: Journal of Ovarian Research 2020 13:63

    Content type: Review

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  10. Malignant transformation such as ovarian squamous cell carcinoma (SCC) in ovarian mature cystic teratoma (OMCT) is a rare tumor. The gene mutation of ovarian SCC remains unclear. We herein report a recurrent c...

    Authors: Xuhui Dong, Lei Yuan and Liangqing Yao

    Citation: Journal of Ovarian Research 2020 13:62

    Content type: Case report

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  11. LncRNA TONSL-AS1 has been characterized as a critical player in gastric cancer. By analyze the TCGA dataset, we observed the upregulation of TONSL-AS1 in ovarian epithelial carcinoma (EOC). We therefore invest...

    Authors: Yan Liu, Ling Li, Xiangyang Wang, Ping Wang and Zhongxian Wang

    Citation: Journal of Ovarian Research 2020 13:60

    Content type: Research

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  12. Biomarkers are needed to guide treatment decisions in recurrent ovarian cancer, as a high proportion of patients do not benefit from treatments. Data on immune subsets in patients receiving chemotherapy are sc...

    Authors: Jon Røikjær Henriksen, Line Nederby, Frede Donskov, Marianne Waldstrøm, Parvin Adimi, Anders Jakobsen and Karina Dahl Steffensen

    Citation: Journal of Ovarian Research 2020 13:59

    Content type: Research

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  13. A hallmark of epithelial ovarian cancer (EOC) metastasis is the process of spheroid formation, whereby tumour cells aggregate into 3D structures while in suspension in the peritoneal cavity. EOC spheroids are ...

    Authors: Jeremi Laski, Bipradeb Singha, Xu Wang, Yudith Ramos Valdés, Olga Collins and Trevor G. Shepherd

    Citation: Journal of Ovarian Research 2020 13:58

    Content type: Research

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  14. The therapeutic value of systematic lymphadenectomy during debulking surgery for ovarian cancer remains controversial. We conduct this meta-analysis to evaluate the significance of systematic lymphadenectomy i...

    Authors: Qingqing Lin, Wenchao Liu, Song Xu, Juan Li and Jinyi Tong

    Citation: Journal of Ovarian Research 2020 13:56

    Content type: Research

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  15. Thrombocytosis is related to tumor stage and survival in ovarian cancer in addition to the common complications of malignant diseases, such as anemia and inflammation. The aim of our study was to clarify the p...

    Authors: Sari Nakao, Takeo Minaguchi, Hiroya Itagaki, Yoshihiko Hosokawa, Ayumi Shikama, Nobutaka Tasaka, Azusa Akiyama, Hiroyuki Ochi, Koji Matsumoto and Toyomi Satoh

    Citation: Journal of Ovarian Research 2020 13:55

    Content type: Research

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  16. Central nervous system (CNS) spreading from epithelial ovarian carcinoma (EOC) is an uncommon but increasing phenomenon. We previously reported in a small series of 11 patients a correlation between Androgen R...

    Authors: Gloria Mittica, Margherita Goia, Angela Gambino, Giulia Scotto, Mattia Fonte, Rebecca Senetta, Massimo Aglietta, Fulvio Borella, Anna Sapino, Dionyssios Katsaros, Furio Maggiorotto, Eleonora Ghisoni, Gaia Giannone, Valentina Tuninetti, Sofia Genta, Chiara Eusebi…

    Citation: Journal of Ovarian Research 2020 13:53

    Content type: Research

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  17. Most studies have mainly focused on the effects of the sperm DNA fragmentation index (DFI) on fertilization, embryonic developmental potential and aneuploidy, pregnancy and abortion rates after in vitro fertil...

    Authors: Linjun Chen, Junshun Fang, Weihua Jiang, Jie Wang and Dong Li

    Citation: Journal of Ovarian Research 2020 13:52

    Content type: Research

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  18. MicroRNAs (miRNAs) have been implicated to play a vital role in development, differentiation, cell proliferation and apoptosis. However, which miRNAs are actually associated with endometriosis-associated ovari...

    Authors: Natsuho Nakamura, Yoshito Terai, Misa Nunode, Kana Kokunai, Hiromi Konishi, Sayaka Taga, Mayumi Nakamura, Masae Yoo, Masami Hayashi, Yoshiki Yamashita and Masahide Ohmichi

    Citation: Journal of Ovarian Research 2020 13:51

    Content type: Research

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  19. It is estimated that more than 20% of ovarian cancer cases are associated with a genetic predisposition that is only partially explained by germline mutations in the BRCA1 and BRCA2 genes. Recently, several piece...

    Authors: Malwina Suszynska, Magdalena Ratajska and Piotr Kozlowski

    Citation: Journal of Ovarian Research 2020 13:50

    Content type: Research

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  20. Premature ovarian insufficiency (POI), which is characterized by early menopause before the age of 40 years, affects approximately 1–5% of women. Cytoplasmic polyadenylation element binding protein 1 (CPEB1) i...

    Authors: Wenlin Jiao, Shidou Zhao, Ran Liu, Ting Guo and Yingying Qin

    Citation: Journal of Ovarian Research 2020 13:49

    Content type: Research

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  21. The cancer cell metastasis and the acquisition of chemotherapy resistance remain huge challenge for ovarian cancer treatment. Previously, N-myc downstream-regulated gene 2 (NDRG2) serves as a tumor suppressor ...

    Authors: Fenhong Kang, Yanlong Wang, Yaping Luo and Yongjun Zhang

    Citation: Journal of Ovarian Research 2020 13:48

    Content type: Research

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  22. Ovarian cancer (OC) is a leading cause of cancer-related death in women, and thus an accurate diagnosis of the predisposition and its early detection is necessary. The aims of this study were to determine whet...

    Authors: Kazuya Maeda, Hiroshi Sasaki, Shoko Ueda, Shunsuke Miyamoto, Shinichi Terada, Hiromi Konishi, Yuhei Kogata, Keisuke Ashihara, Satoe Fujiwara, Yoshimichi Tanaka, Tomohito Tanaka, Masami Hayashi, Yuko Ito, Yoichi Kondo, Takahiro Ochiya and Masahide Ohmichi

    Citation: Journal of Ovarian Research 2020 13:47

    Content type: Research

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  23. For patients presenting with adnexal mass, it is important to correctly distinguish whether the mass is benign or malignant for the purpose of precise and timely referral and implication of correct line of man...

    Authors: Abha Hada, Li-ping Han, Yanyan Chen, Qing-hong Hu, Yidan Yuan and Liya Liu

    Citation: Journal of Ovarian Research 2020 13:46

    Content type: Research

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  24. Currently, the function and mechanisms of long non-coding RNAs (lncRNAs) involved in the metastasis of epithelial ovarian cancer (EOC), especially those of the lncRNAs participated in the epithelial-mesenchyma...

    Authors: Xiaojing Lin, Xiaoyan Tang, Tingting Zheng, Junjun Qiu and Keqin Hua

    Citation: Journal of Ovarian Research 2020 13:45

    Content type: Research

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  25. There are about 2.4 hundred thousand new cases and 1.5 hundred thousand deaths of ovarian cancer (OC) annually in the world. Chronic inflammation is a risk factor for OC. C-X-C motif chemokine ligand 1 (CXCL1)...

    Authors: Man Guo, Chao Xu, Yan-Zhe Chen, Qi-Wen Sun, Xin-Ying Zhao, Xin Liu, Yi Yang, Yi-Yan Hu, Fei-Feng Li and Shu-Lin Liu

    Citation: Journal of Ovarian Research 2020 13:43

    Content type: Research

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  26. Variations in many genes may lead to the occurrence of oocyte maturation defects. To investigate the genetic basis of oocyte maturation defects, we performed clinical and genetic analysis of a pedigree.

    Authors: Qiong Xing, Ruyi Wang, Beili Chen, Lin Li, Hong Pan, Tengyan Li, Xu Ma, Yunxia Cao and Binbin Wang

    Citation: Journal of Ovarian Research 2020 13:42

    Content type: Research

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  27. Premature ovarian insufficiency (POI) is a severe disorder of female infertility, characterized by 4–6 months of amenorrhea before the age of 40 years, with elevated follicle stimulating hormone (FSH) levels (...

    Authors: Lin Li, Fan Feng, Minying Zhao, Tengyan Li, Wentao Yue, Xu Ma, Binbin Wang and Chenghong Yin

    Citation: Journal of Ovarian Research 2020 13:41

    Content type: Research

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  28. Our previous studies showed the expression of herpes virus entry mediator (HVEM) is high in ovarian cancer samples and correlated to the patient clinic pathological features. As we all know, the hypoxic enviro...

    Authors: Liyan Duan, Jie Tao, Xiaoqian Yang, Lei Ye, Yueqian Wu, Qizhi He, Yingchun Duan, Li Chen and Jianlong Zhu

    Citation: Journal of Ovarian Research 2020 13:40

    Content type: Research

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  29. A recent study published in the journal Nature Communications from Karolinska Institute, Sweden was unable to detect stem cells in adult human ovarian cortex by single-cell RNAseq and by studying cell surface ant...

    Authors: Deepa Bhartiya and Diksha Sharma

    Citation: Journal of Ovarian Research 2020 13:39

    Content type: Brief communication

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  30. Ovarian clear cell carcinoma (OCCC) is the second most common ovarian cancer after serous carcinoma in Southeast Asia. OCCC has a more unfavourable clinical outcome due to a poor response to platinum-based che...

    Authors: Huimei Zhou, Qian Liu, Xiaohua Shi, Yue Liu, Dongyan Cao and Jiaxin Yang

    Citation: Journal of Ovarian Research 2020 13:38

    Content type: Research

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  31. Although lncRNA CTBP1-AS2 has been functionally analyzed only in cardiomyocyte hypertrophy and diabetes, analysis of TCGA dataset revealed its downregulation in endometrial carcinoma (EC), indicating its invol...

    Authors: Qing-an-zi Wang, Yongxiu Yang and Xiaolei Liang

    Citation: Journal of Ovarian Research 2020 13:37

    Content type: Research

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  32. Women with irregular menstruation should be considered to benefit from the ovarian stimulation. However, most literature did not separate ovulatory disorders from normal menstrual cycles. Our purpose was to as...

    Authors: Sichen Li, Yuxia He, Mingzhu Cao, Hanyan Liu and Jianqiao Liu

    Citation: Journal of Ovarian Research 2020 13:36

    Content type: Research

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  33. Epithelial ovarian cancer (EOC) is highly lethal gynecological cancer. Forkhead Box Protein C2 (FOXC2) promotes occurrence and development of various malignant tumors. The present study is aimed at exploring t...

    Authors: Zhijiao Zhou, Xiang Ou, Qiong Zou, Ling Chu, Xiyun Quan, Yong Chen and Yang Liu

    Citation: Journal of Ovarian Research 2020 13:34

    Content type: Research

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  34. Primary ovarian signet-ring cell carcinoma is extremely rare, with only five recent case reports. Almost all reported cases of ovarian signet-ring cell carcinoma have been treated with TC therapy and none have...

    Authors: Tadahiro Shoji, Ryosuke Takeshita, Tatsunori Saito, Takeshi Aida, Shunichi Sasou and Tsukasa Baba

    Citation: Journal of Ovarian Research 2020 13:33

    Content type: Case report

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  35. Polycystic ovary syndrome (PCOS) is a complex reproduction and endocrine disorder of women in the reproductive age. Spearmint (Mentha spicata L.) has anti-androgenic activity and flaxseed (Linum usitatissimum L.)...

    Authors: Mina Mehraban, Gholamali Jelodar and Farhad Rahmanifar

    Citation: Journal of Ovarian Research 2020 13:32

    Content type: Research

    Published on:

  36. As one of the main gynecological cancers, ovarian cancer (OC) has an unfavourable outcomes owing to its high recurrence and metastasis rate. Our previous studies have revealed that LINC01296 functions as an on...

    Authors: Hui Xu, Hong-Luan Mao, Xin-Rui Zhao, Yue Li and Pei-Shu Liu

    Citation: Journal of Ovarian Research 2020 13:31

    Content type: Research

    Published on:

  37. Olaparib, a poly ADP-ribose polymerase (PARP) inhibitor, has proven to be effective and safe as maintenance therapy and multiline therapy in ovarian cancer, especially in patients with BRCA mutations. This stu...

    Authors: Jing Ni, Rui Zhou, Xianzhong Cheng, Xia Xu, Wenwen Guo and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2020 13:29

    Content type: Case report

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  38. The original article [1] contains errors in Fig. 3C, Results and Discussion.

    Authors: Huan Wu, Rongrong Li, Zhiwei Zhang, Huiyang Jiang, Hanlin Ma, Cunzhong Yuan, Chenggong Sun, Yingwei Li and Beihua Kong

    Citation: Journal of Ovarian Research 2020 13:28

    Content type: Correction

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    The original article was published in Journal of Ovarian Research 2019 12:125

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