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  1. Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder of heterogeneous nature. Secreted frizzled-related protein (SFRP) 5 is an anti-inflammatory adipokine implicated in metabolic homeostasis. We ai...

    Authors: Yi Zhang, Yuxin Ran, Lingna Kong, Lihong Geng, Hua Huang, Hongying Zhang, Jun Hu, Hongbo Qi and Ying Chen

    Citation: Journal of Ovarian Research 2021 14:97

    Content type: Research

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  2. Ovarian cancer (OC) is considered the most lethal gynecological cancer, of which more than 65% cases are diagnosed in advanced stages, requiring platinum-based neoadjuvant chemotherapy (NACT).

    Authors: Jorge A. Alegría-Baños, José C. Jiménez-López, Arely Vergara-Castañeda, David F. Cantú de León, Alejandro Mohar-Betancourt, Delia Pérez-Montiel, Gisela Sánchez-Domínguez, Mariana García-Villarejo, César Olivares-Pérez, Ángel Hernández-Constantino, Acitlalin González-Santiago, Miguel Clara-Altamirano, Liz Arela-Quispe and Diddier Prada-Ortega

    Citation: Journal of Ovarian Research 2021 14:96

    Content type: Research

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  3. Cryopreservation and transplantation of ovarian tissue (OTCTP) represent a promising fertility preservation technique for prepubertal patients or for patients requiring urgent oncological management. However, ...

    Authors: Carmen Terren, Michelle Nisolle and Carine Munaut

    Citation: Journal of Ovarian Research 2021 14:95

    Content type: Research

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  4. Laser-assisted hatching (LAH) has been widely applied to facilitate blastocyst hatching in IVF-ET treatment, however, the effect of LAH on subsequent development and clinical outcomes of the lower grade cleava...

    Authors: Weihai Xu, Ling Zhang, Lin Zhang, Zhen Jin, Limei Wu, Shishi Li and Jing Shu

    Citation: Journal of Ovarian Research 2021 14:94

    Content type: Research

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  5. The aim of this meta-analysis was to assess the effectiveness and safety of secondary cytoreductive surgery plus chemotherapy (SCS + CT) in recurrent ovarian cancer (ROC). Our secondary purpose was to analyze ...

    Authors: Ting Ding, Dan Tang and Mingrong Xi

    Citation: Journal of Ovarian Research 2021 14:93

    Content type: Review

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  6. Ovarian cancer is one of the most common gynecological tumors, and among gynecological tumors, its incidence and mortality rates are fairly high. However, the pathogenesis of ovarian cancer is not clear. The p...

    Authors: Cuicui Dong, Xin Tian, Fucheng He, Jiayi Zhang, Xiaojian Cui, Qin He, Ping Si and Yongming Shen

    Citation: Journal of Ovarian Research 2021 14:92

    Content type: Research

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  7. Biochemical recurrence is defined as only rising CA-125 but no radiographic evidence of disease; noteworthily, it generally precedes the onset of clinical evidence. Now treatment strategies of biochemical recu...

    Authors: Zhongyu Wang, Yake Huang, Ling Long, Li Zhou, Yan Huang, Lei Gan, Aimin Pu, Sufen Li and Rongkai Xie

    Citation: Journal of Ovarian Research 2021 14:91

    Content type: Research

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  8. Aberrant expression of microRNAs (miRNAs) contributes to the development of high grade serous ovarian cancer (HGSOC). However, the molecular mechanism by which miRNA-585-3p mediates high-grade serous ovarian c...

    Authors: Xiaoyuan Lu, Guilin Li, Sicong Liu, Haihong Wang and Buze Chen

    Citation: Journal of Ovarian Research 2021 14:90

    Content type: Research

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  9. For young borderline ovarian tumor (BOT) patients, preservation of the uterus was incorporated as an accepted option into treatment guidelines. For the endometrioid subtype (eBOT) however, adequate histologica...

    Authors: Juliane Reichenbach, Elisa Schmoeckel, Sven Mahner and Fabian Trillsch

    Citation: Journal of Ovarian Research 2021 14:89

    Content type: Case report

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  10. Serous endometrial intraepithelial carcinoma (SEIC) is now considered to represent an early stage of uterine serous carcinoma (USC). It is an intraepithelial lesion but has been reported to cause extrauterine ...

    Authors: Maho Shimizu, Keitaro Yamanaka, Maho Azumi, Masako Tomimoto, Keiichi Washio, Ryosuke Takahashi, Satoshi Nagamata, Yuka Murata, Yui Yamasaki and Yoshito Terai

    Citation: Journal of Ovarian Research 2021 14:87

    Content type: Case report

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  11. Premature ovarian insufficiency (POI) is an ovarian defect characterized by primary or secondary amenorrhea, hypergonadotropism and hypoestrogenism which occurs before the age of 40 years with a major genetic ...

    Authors: Eleonora Ferrarini, Giuseppina De Marco, Francesca Orsolini, Elena Gianetti, Elena Benelli, Franca Fruzzetti, Tommaso Simoncini, Patrizia Agretti and Massimo Tonacchera

    Citation: Journal of Ovarian Research 2021 14:85

    Content type: Research

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  12. The p38MAPK family of Mitogen Activated Protein Kinases are a group of signalling molecules involved in cell growth, survival, proliferation and differentiation. The widely studied p38α isoform is ubiquitously...

    Authors: Periklis Katopodis, Rachel Kerslake, Athanasios Zikopoulos, Nefeli Beri and Vladimir Anikin

    Citation: Journal of Ovarian Research 2021 14:84

    Content type: Research

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  13. Blastocyst development by extended culture in vitro allows the embryos to ‘select’ themselves, thus successful growth to the blastocyst stage is a reflection of the developmental competence of cleavage stage e...

    Authors: Jianyuan Song, Cuicui Duan, Wangyu Cai and Jian Xu

    Citation: Journal of Ovarian Research 2021 14:83

    Content type: Research

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  14. Hilus cell tumours is considered an uncommon branch of androgen producing neoplasms that accounts for < 5% of all ovarian tumours. They are mostly benign and have characteristic gross and microscopic features....

    Authors: Haider Ali Malakzai, Jamshid Abdul-Ghafar, Abdul Sami Ibrahimkhil and Ahmed Maseh Haidary

    Citation: Journal of Ovarian Research 2021 14:81

    Content type: Case report

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  15. To explore the relationship between ERCC1 rs11615 polymorphism and chemosensitivity to platinum drugs in ovarian cancer by the method of meta-analysis.

    Authors: Yuqiang Zhang, Sufen Cao, Chunyu Zhuang, Jiacheng Chen, Xiaojing Chen, Hong Sun, Shengying Lin and Bailang Lin

    Citation: Journal of Ovarian Research 2021 14:80

    Content type: Review

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  16. Polycystic ovary syndrome (PCOS) is a common endocrine disease in women of reproductive age. Multiple studies have shown that long non-coding RNAs (lncRNA) and microRNAs (miRNA) play a role in PCOS. This study...

    Authors: Zhihong Zhang, Min Sang, Siqin Liu, Jing Shao and Yunjiang Cai

    Citation: Journal of Ovarian Research 2021 14:79

    Content type: Research

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  17. Although preimplantation genetic test (PGT) has been used worldwide, few studies investigated the effect of trophectoderm biopsy of blastocysts on early embryo development. This study aimed to investigate whet...

    Authors: Yixuan Wu, Ying Ying, Mingzhu Cao, Jianqiao Liu and Haiying Liu

    Citation: Journal of Ovarian Research 2021 14:78

    Content type: Research

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  18. We aimed to explore role of lncRNA PAX-interacting protein 1-antisense RNA1 (PAXIP1-AS1) in ovarian cancer (OC). RT-qPCR analysis identified upregulation of PAXIP1-AS1 in OC cell lines. Functionally, PAXIP1-AS...

    Authors: Yimin Ma and Wei Zheng

    Citation: Journal of Ovarian Research 2021 14:76

    Content type: Research

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  19. Ovarian cancer is the seventh most common cancer in women and the second most reason of gynecologic cancer-related death. Growing evidence showed that exosomal miRNA plays a crucial role in the progression of ...

    Authors: Jun Xiong, Xiaoju He, Yuanyuan Xu, Wei Zhang and Fen Fu

    Citation: Journal of Ovarian Research 2021 14:74

    Content type: Research

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  20. Microcystic stromal tumor (MCST) of the ovary is an extremely rare subtype of sex cord-stromal neoplasm first described by Irving and Young in 2009. Tumors from all previously reported cases (fewer than 40 tot...

    Authors: Xiaxia Man, Zhentong Wei, Baogang Wang, Wanying Li, Lingling Tong, Liang Guo and Songling Zhang

    Citation: Journal of Ovarian Research 2021 14:73

    Content type: Case report

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  21. To determine the state of current practice and to reach a consensus on recommendations for the management of advanced ovarian cancer using a Delphi survey with a group of Spanish gynecologists and medical onco...

    Authors: Andres Redondo, Ana Oaknin, Maria Jesus Rubio, Maria-Pilar Barretina-Ginesta, Ana de Juan, Luis Manso, Ignacio Romero, Cristina Martin-Lorente, Andres Poveda and Antonio Gonzalez-Martin

    Citation: Journal of Ovarian Research 2021 14:72

    Content type: Research

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  22. Karyopherin α-2 (KPNA2) is a member of karyopherin family, which is proved to be responsible for the import or export of cargo proteins. Studies have determined that KPNA2 is associated with the development an...

    Authors: Xiangrong Cui, Honghong Wang, Xueqing Wu, Kai Huo and Xuan Jing

    Citation: Journal of Ovarian Research 2021 14:71

    Content type: Research

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  23. Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mainly attacks the respiratory system and is characterized by pneumonia, cytokine storm, coagulation d...

    Authors: Osman A. Dufailu, Afrakoma Afriyie-Asante, Bernard Gyan, David Adu Kwabena, Helena Yeboah, Frank Ntiakoh and Meshach Asare-Werehene

    Citation: Journal of Ovarian Research 2021 14:70

    Content type: Review

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  24. Cyclin-dependent kinase 9 (CDK9) has been shown to play an important role in tumorigenesis of several malignancies. However, the expression of CDK9 in ovarian cancer from Middle Eastern ethnicity remains unknown.

    Authors: Sandeep Kumar Parvathareddy, Abdul K. Siraj, Tariq Masoodi, Padmanaban Annaiyappanaidu, Ismail A. Al-Badawi, Fouad Al-Dayel and Khawla S. Al-Kuraya

    Citation: Journal of Ovarian Research 2021 14:69

    Content type: Research

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  25. Niraparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, is approved for first/second-line maintenance treatment of ovarian cancer patients with complete or partial response to platinum-based chemotherapy, ...

    Authors: Jing Ni, Xianzhong Cheng, Qian Zhao, Zhiqin Dai, Xia Xu, Wenwen Guo, Hongyuan Gu, Rui Zhou, Yan Wang and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2021 14:68

    Content type: Research

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  26. LAMA3 is a widely studied methylated gene in multiple tumors, but the relationship between chemotherapy resistance in ovarian cancer is unclear. In this study, LAMA3 methylation was predicted by bioinformatics...

    Authors: Li-yuan Feng, Yong-zhi Huang, Wei Zhang and Li Li

    Citation: Journal of Ovarian Research 2021 14:67

    Content type: Research

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  27. Dysregulation of immune response is associated with development of endometriosis. The study aim was to evaluate effect of combined oral contraceptive pills (COCs) consisting of ethinyl estradiol (EE) and desog...

    Authors: Wanwisa Waiyaput, Keerati Wattanakamolchai, Yada Tingthanatikul, Srithean Lertvikool, Siriluk Tantanavipas, Kanthanadon Dittharot, Morakot Sroyraya and Areepan Sophonsritsuk

    Citation: Journal of Ovarian Research 2021 14:66

    Content type: Research

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  28. Polycystic ovary syndrome (PCOS) is a multifactorial endocrinopathy that affects reproduction and metabolism. Mammalian target of rapamycin (mTOR) has been shown to participate in female reproduction under phy...

    Authors: Zaixin Guo, Xiaohan Chen, Penghui Feng and Qi Yu

    Citation: Journal of Ovarian Research 2021 14:64

    Content type: Research

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  29. This study aimed to identify the clinical characteristics of Chinese patients with ovarian endometrioid carcinoma (EC) and clear cell carcinoma (CCC) and to assess the impact of concurrent endometriosis on thi...

    Authors: Ling Zhou, Liqing Yao, Lin Dai, Honglan Zhu, Xue Ye, Shang Wang, Hongyan Cheng, Ruiqiong Ma, Huiping Liu, Heng Cui and Xiaohong Chang

    Citation: Journal of Ovarian Research 2021 14:63

    Content type: Research

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  30. Professional society guidelines recommend risk-reducing salpingo-oophorectomy (RRSO) for women with pathogenic variants (PVs) in ovarian cancer-risk genes. Personalization of that intervention is based on gene...

    Authors: Shelly Cummings, Susana San Roman, Jennifer Saam, Ryan Bernhisel, Krystal Brown, Johnathan M. Lancaster and Lydia Usha

    Citation: Journal of Ovarian Research 2021 14:61

    Content type: Research

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  31. Abnormally expressed in various tumors, long non-coding RNAs (lncRNAs) feature prominently in tumor development, yet little is still known regarding the functional roles of lncRNA AFAP1 antisense RNA 1 (AFAP1-...

    Authors: Bao Liu, Li Yan, Yugang Chi, Yuhan Sun and Xiaoyu Yang

    Citation: Journal of Ovarian Research 2021 14:60

    Content type: Research

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  32. Exosomal miRNAs regulate gene expression and play important roles in several diseases. We used exosomal miRNA profiling to investigate diagnostic biomarkers of epithelial ovarian cancer (EOC).

    Authors: Jingjing Liu, Jigeun Yoo, Jung Yoon Ho, Yuyeon Jung, Sanha Lee, Soo Young Hur and Youn Jin Choi

    Citation: Journal of Ovarian Research 2021 14:59

    Content type: Research

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  33. Polycystic Ovary Syndrome (PCOS) is associated with high levels of phsychological implications and detriments to Quality of Life (QoL). The aim of this study was to assess Health- Related Quality of Life (HRQo...

    Authors: Bahadori Fatemeh, Jahanian Sadatmahalleh Shahideh and Mirzaei Negin

    Citation: Journal of Ovarian Research 2021 14:57

    Content type: Research

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  34. Pure ovarian choriocarcinoma can be gestational or nongestational in origin. Nongestational pure ovarian choriocarcinoma is extremely rare and the prognosis is thought to be worse than that of the gestational ...

    Authors: Kimihiro Nishino, Eiko Yamamoto, Yoshiki Ikeda, Kaoru Niimi, Toshimichi Yamamoto and Hiroaki Kajiyama

    Citation: Journal of Ovarian Research 2021 14:56

    Content type: Case report

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  35. Ovarian cancer is the most fatal gynecologic malignancy in the United States. While chemotherapy is effective in the vast majority of ovarian cancer patients, recurrence and resistance to standard systemic the...

    Authors: Katie K. Crean-Tate, Chad Braley, Goutam Dey, Emily Esakov, Caner Saygin, Alexandria Trestan, Daniel J. Silver, Soumya M. Turaga, Elizabeth V. Connor, Robert DeBernardo, Chad M. Michener, Peter G. Rose, Justin Lathia and Ofer Reizes

    Citation: Journal of Ovarian Research 2021 14:55

    Content type: Research

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  36. Nuclear small RNAs have emerged as an important subset of non-coding RNA species that are capable of regulating gene expression. A type of small RNA, microRNA (miRNA) have been shown to regulate development of...

    Authors: Derek Toms, Bo Pan, Yinshan Bai and Julang Li

    Citation: Journal of Ovarian Research 2021 14:54

    Content type: Research

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  37. Ovarian sex cord stromal tumours (OSCSTs) are rare ovarian tumours and include different histopathologic subtypes. This study aimed to analyse the clinical and sonographic characteristics of different histopat...

    Authors: Mei-jiao Jiang, Qian Le, Bo-wen Yang, Fei Yuan and Hui Chen

    Citation: Journal of Ovarian Research 2021 14:53

    Content type: Research

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  38. The clinical implication of the increased serum progesterone level on the day of HCG administration in assisted reproduction treatment (ART) is still controversial. The current study aimed to compare the predi...

    Authors: Ahmad Mahran, Mohammed Khairy, Reham Elkhateeb, Abdel Rahman Hegazy, Ayman Abdelmeged, Gaber El-Saber Batiha, Khalaf F. Alsharif, Helal F. Hetta and Haitham Ahmed Bahaa

    Citation: Journal of Ovarian Research 2021 14:52

    Content type: Research

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  39. High-quality single blastocyst transfer (SBT) is increasingly recommended to patients because of its acceptable pregnancy outcomes and significantly reduced multiple pregnancy rate compared to double blastocys...

    Authors: Yuxia He, Shiping Chen, Jianqiao Liu, Xiangjin Kang and Haiying Liu

    Citation: Journal of Ovarian Research 2021 14:51

    Content type: Research

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  40. Limited studies have reported the relationship between intestinal flora dysbiosis and clinical characteristics in polycystic ovary syndrome (PCOS). However, the structure and characteristics of gut microbiota in ...

    Authors: Fangfang He and Yumei Li

    Citation: Journal of Ovarian Research 2021 14:50

    Content type: Research

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  41. Primary debulking surgery (PDS) is the main treatment for patients with advanced ovarian cancer, and neoadjuvant chemotherapy (NACT) is for bulky stage III-IV patients who are poor surgical candidates and/or f...

    Authors: Dengfeng Wang, Guonan Zhang, Chunrong Peng, Yu Shi and Xunwei Shi

    Citation: Journal of Ovarian Research 2021 14:49

    Content type: Research

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  42. Polycystic ovary syndrome (PCOS) is the most common hormonal disorder among reproductive-aged women worldwide, however, the mechanisms and progression of PCOS still unclear due to its heterogeneous nature. Usi...

    Authors: Dongyong Yang, Yanqing Wang, Yajing Zheng, Fangfang Dai, Shiyi Liu, Mengqin Yuan, Zhimin Deng, Anyu Bao and Yanxiang Cheng

    Citation: Journal of Ovarian Research 2021 14:48

    Content type: Research

    Published on:

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