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Table 1 Patients characteristics.

From: Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients

  ALL PATIENTS TP-TREATED GROUP PC/PAC-TREATED GROUP
  N = 435 N = 191 N = 244
Age (years)    
Range 20-78 20-78 24-77
Mean 54.3 54.9 53.9
FIGO stage    
IIB, IIC 27 (6%) 10 (5%) 17 (7%)
IIIA, IIIB 82 (19%) 26 (14%) 56 (23%)
IIIC 277 (64%) 136 (71%) 141 (58%)
IV 49 (11%) 19 (10%) 30 (12%)
Residual tumour size    
0 87 (20%) 35 (18%) 52 (21%)
≤ 2 cm 141 (32%) 77 (40%) 64 (26%)
> 2 cm 207 (48%) 79 (42%) 128 (53%)
Histological type    
serous 334 (77%) 142 (74%) 192 (79%)
endometrioid 22 (5%) 8 (4%) 14 (6%)
clear cell 15 (3%) 4 (2%) 11 (4%)
undifferentiated 33 (8%) 20 (11%) 13 (5%)
other types 31 (7%) 17 (9%) 14 (6%)
Histological grade    
G 2 54 (13%) 24 (12%) 30 (12%)
G 3 263 (60%) 110 (58%) 153 (63%)
G 4 118 (27%) 57 (30%) 61 (25%)
Response to chemotherapy    
complete remission 257 (59%) 124 (65%) 133 (55%)
partial remission/no change 112 (26%) 62 (32%) 50 (20%)
progression 66 (15%) 5 (3%) 61 (25%)
Platinum sensitive 129 (30%) 65 (34%) 64 (26%)
Highly platinum sensitive 83 (19%) 40 (21%) 43 (18%)
Platinum resistant 223 (51%) 86 (45%) 137 (56%)
Number of patients at risk (OS)    
1 year 389 (89%) 180 (94%) 209 (86%)
2 years 276 (63%) 141 (74%) 135 (57%)
3 years 172 (39%) 83 (43%) 89 (36%)
4 years 116 (27%) 53 (28%) 63 (26%)
5 years 76 (17%) 31 (16%) 45 (18%)
Number of patients at risk (DFS)    
1 years 143 (56%) 70 (56%) 73 (55%)
2 years 83 (32%) 40 (32%) 43 (32%)
3 years 61 (24%) 27 (22%) 34 (26%)
4 years 43 (17%) 17 (14%) 26 (19%)
5 years 28 (11%) 10 (8%) 18 (13%)
Follow-up time    
Range (month) 4.4-198.3 4.8-100.6 4.4-198.3
mean 30 32.2 27.5
Outcome    
NED 45 (10%) 27 (14%) 18 (7%)
AWD 45 (10%) 35 (18%) 10 (4%)
DOD 335 (77%) 124 (65%) 211 (87%)
DOC 10 (3%) 5 (3%) 5 (2%)
  1. PC- cyclophosphamide and cisplatin, PAC-PC plus doxorubicin, TP-taxane-platinum therapy; NED-no evidence of disease, AWD-alive with disease, DOD-died of disease, DOC-died of other causes; OS-overall survival, DFS-disease free survival