Table 1 Top 20 genes down- and up-regulated in each drug resistance phenotype
Down-regulated | Up-Regulated | ||||
|---|---|---|---|---|---|
Cisplatin | Doxorubicin | Paclitaxel | Cisplatin | Doxorubicin | Paclitaxel |
CLCA1 | APOE | PRSS3 | C20orf75 | RPIB9 | APOA1 |
CCL26 | MSMB | CCL26 | WFS1 | IL8 | GAGE6 |
RFTN1 | CCL26 | PRSS2 | GNG11 | TXNIP | XAGE1 |
TCN1 | ANKRD38 | PRSS1 | MFGE8 | ABCB1 | SCRG1 |
SCARF2 | CDH11 | RHOU | CEACAM6 | PRSS2 | GAGE7B |
MAPK13 | PRSS8 | TCN1 | MTMR11 | PRSS3 | ALB |
LDHA | APOC1 | PRNP | PSG11 | GNG11 | VSIG1 |
ECAT11 | ITIH2 | FKBP11 | PAM | CD96 | REG4 |
SPP1 | MAF | MSMB | NOS3 | LPXN | AFP |
DDIT4L | FABP5 | LCP1 | GAGE6 | SGK | FAM112B |
APOE | IGSF4 | NNMT | CLYBL | MLLT11 | RP1-32F7.2 |
SPOCK2 | SOX21 | MAF | GAGE7B | CFB | ADH1A |
NINJ2 | NPC2 | ECHDC2 | SERPINE2 | GADD45A | NMU |
THBS1 | SCD | ANKRD38 | CECR5 | MYH4 | CTAG2 |
SOX21 | MT1F | WDR72 | ADAM15 | CXCL6 | ADH1C |
CD44 | RRAGD | CD9 | DPYSL3 | GABARAPL1 | AMBP |
RGS4 | SPOCK2 | MATN2 | REG4 | POU2F2 | MMP1 |
DDIT4 | RENBP | RRAGD | GALR2 | PRSS1 | PRTFDC1 |
IGF2 | SPINT2 | SERPIND1 | TFF2 | CYR61 | GAGE5 |
GPC3 | RFTN1 | A2M | EEF1A2 | TNFRSF11B | TSPAN12 |