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Figure 1 | Journal of Ovarian Research

Figure 1

From: Morphology of ovaries in laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1

Figure 1

Ovaries of 2-year-old wild type (WT) mice (A, C, E) and 2-year-old Laron dwarf (GHR/GHBP-KO) mice (B, D, F). In WT mice, the ovarian follicles are missing. Cuboidal epithelium on the ovarian surface (arrow) and large numbers of interstitial cells (IT), blood vessels (BV), macrophages (M), and inflammatory cells (IC) are visible (A, C, E). In contrast, Laron dwarf mouse ovaries are very well developed and all types of follicles are present, including preantral (PAF), antral (AF), and degenerative (DF) follicles, and granulosa cells (asterix) are also visible. Well-organized cuboidal epithelium on the ovarian surface (arrow), macrophages (M), and interstitial tissue (IT) were also observed (B, D, F). H + E staining. Bar = 500μm (A and B), Bar = 200 μm (C and D), Bar = 100 μm (E and F)

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Journal of Ovarian Research

ISSN: 1757-2215

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