Figure 1
From: IGFBP-4 tumor and serum levels are increased across all stages of epithelial ovarian cancer
IGFBP-4 is upregulated in patient serum samples compared to controls. Patient and control serum samples were analyzed by ELISA and IGFBP-4 concentrations determined and graphed (pink bars). Samples with IGFBP-4 levels less than control values are light pink and IGFBP-4 levels greater than controls are dark pink. As a comparison, CA125 levels for patients are graphed in green. Using the standard cutoff of 35 U/ml, CA125 levels were divided into high (dark green) and low (light green). Those patients where IGFBP-4 was a better marker (low CA125 but high IGFBP-4) are indicated with an asterisk.