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Table 1 Resistance values determined by clonogenic assay expressed as IC 50 for each cell line and drug(s)

From: Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel

Resistant line IC 50 of resistant line to either CBN and/or DXL IC 50 of co-cultured control to either CBN and/or DXL Fold resistance. Ratio of IC 50 of resistant line/ co-cultured control
A2780CBN 7.77 x 10-5 M CBN 5.73 x 10-6 M CBN 13.56
  3.62 x 10-10 M DXL 5.76 x 10-10 M DXL 0.63
A2780DXL 3.61 x 10-7 M DXL 8.91 x 10-11 M DXL 4051.63
  2.20 x 10-6 M CBN 6.75 x 10-6 M CBN 0.33
A2780CBNDXL 8.02 x 10-6 M CBN 6.37 x 10-7 M CBN 12.59
  8.02 x 10-9 M DXL 6.37 x 10-10 M DXL  
A2780CBNDXL 2.52 x 10-5 M CBN 2.50 x 10-6 M CBN 10.08
A2780CBNDXL 1.47 x 10-8 M DXL 1.84 x 10-9 M DXL 7.99