Figure 1
From: Current status and implications of microRNAs in ovarian cancer diagnosis and therapy
Oncogenic and tumor suppressor miRNAs in ovarian carcinoma. Based on their function miRNAs can be used for diagnostics and therapeutics. Certain miRNAs such as miR-200 family, let-7 family, miR-21, miR-214 and miR-100 have strong diagnostic/prognostic potential in ovarian cancer. Use of antagonists for oncogenic microRNAs and microRNA replacement therapy for tumor suppressor miRNAs are important tools in miRNA based cancer treatment. EMT-Epithelial to Mesenchymal Transition; NM-Nuclear membrane; PM-Plasma membrane.