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Table 2 miRNA profile of subtypes of ovarian cancer

From: Current status and implications of microRNAs in ovarian cancer diagnosis and therapy

Type of ovarian cancer Up-regulated miRNA Down-regulated miRNA References
Serous miR-200a, miR-200b, miR-200c, miR-141, miR-93, miR-21,miR-519a, miR-214 let7-b, miR-99a, miR-125b, miR-22, miR-31, miR-34a/b/c [42, 47, 51, 86, 102, 106, 108, 109]
Clear Cell miR-519a, miR-182, miR-30a,miR-21, miR-200a, miR-200c miR-100, miR-22, miR-34a/b/c, miR-214 [42, 51, 83, 109]
Mucinous miR-153, miR-485-5p   [109]
Endometrioid miR-200a, miR-200b, miR-200c, miR-141   [42]
  1. Most of the miRNA profiling has been done on the serous and clear cell ovarian carcinoma. miR-200 family stands out as the up-regulated miRNA in most types of ovarian cancer. miR-100 plays a specific role in clear cell ovarian carcinoma.