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Table 1 The clinical and biochemical / hormonal data in women with polycystic ovary syndrome (PCOS) patients and healthy controls

From: Heart type fatty acid binding protein response and subsequent development of atherosclerosis in insulin resistant polycystic ovary syndrome patients

Variable

Women with PCOS (n _ 46)

Healthy controls (n _ 28)

P

Age, years

21.97 ± 4.19

23.42 ± 4.70

0.17

BMI, kg/m2

24.50 ± 5.51

23.77 ± 4.91

0.56

Waist/hip ratio

0.81 ± 0.73

0.81 ± 0.63

0.97

Fasting insulin, μ IU/ml

13.84(4.03-47.97)

10.35(2.1-25.8)

0.007

Fasting glucose, mg/dl

91.23 ± 8.24

89.07 ± 9.85

0.31

HOMA-IR

3.21(0.38-12.25)

2.23(0.47-6.43)

0.011

Total cholesterol, mg/dl

173.63 ± 29.41

154.46 ± 26.74

0.006

Triglyceride, mg/dl

111.65 ± 52.80

78.53 ± 30.30

0.002

HDL-C, mg/dl

51.47 ± 12.36

50.78 ± 11.68

0.81

LDL-C, mg/dl

99.68 ± 26.60

87.62 ± 22.58

0.04

hsCRP, mg/L

1.33(0.15-15.8)

0.97(0.15-9)

0.35

TSH, μ IU/ml

2.19 ± 0.96

1.72 ± 0.81

0,03

FSH, m IU/ml

5.49 ± 1.71

5.98 ± 1.86

0.25

LH, m IU/ml

5.69 ± 1.84

5.63 ± 2.25

0.90

Estradiol, pg/ml

40.68 ± 23.25

71.12 ± 42.00

<0.001

Free testosterone,pg/ml

2.99 ± 1.09

1.58 ± 0.51

<0.001

Total testosterone, ng/ml

0.56 ± 0.27

0.41 ± 0.14

0.01

17-OHprogesterone,ng/ml

1.45 ± 0.60

0.98 ± 0.57

0.002

DHEAS, μq/dl

292.60 ± 138.54

175.28 ± 81.63

<0.001

CIMT, mm

0.42 ± 0.056

0.37 ± 0.061

<0,001

HFABP, ng/dl

39.87(22.88-135.12)

35.64(17.86- 79.97)

0.419

  1. BMI body mass index, HOMA-IR homeostasis model assessment insulin resistance index, HDL-C high density lipoprotein cholesterol, LDL-C LOW density lipoprotein cholesterol, hs-CRP high-sensitive C- reactive protein, TSH thyroid stimulating hormone, FSH follicle-stimulating hormone, LH luteinizing hormone, DHEAS dehydroepiandrosterone sulfate, CIMT carotid intima media thickness, HFABP heart fatty acid binding protein.