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Table 2 Selected genes shown to be differentially expressed between Foc3 and MFOC3 cells by transcriptomic profiling.

From: Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination

Downregulated in MFOC3
Gene Symbol Gene Name Fold Change Function
KRT19 Keratin 19 0.10 cytoskeleton
KRT14 Keratin 14 0.13 cytoskeleton
ITGB8 Integrin beta 8 0.19 cell and matrix adhesion
KRT13 Keratin 18 0.24 cytoskeleton
KRT18 Keratin 13 0.30 cytoskeleton
CASP1 Caspase 1 0.33 IL1beta convertase
ITGA9 Integrin alpha 9 0.39 cell and matrix adhesion
ESR1 Estrogen receptor 1 0.41 hormone receptor
NME1 Non-metastatic protein 1 0.49 inhibitor of metastasis
Upregulated in MFOC3
Gene Symbol Gene Name Fold Change Function
PAI2 Plasminogen activator inhibitor type II 25.56 proteolytic enzyme
IL1B Interleukin 1beta 11.11 cytokine
TNF Tumor necrosis factor 7.88 cytokine
API2 Apoptosis inhibitor 2 7.44 inhibition of apoptosis
TGFB1 Transforming growth factor 5.30 cell adhesion regulation
PLAU Plasminogen activator, urokinase 4.50 proteolytic enzyme
FGFR1 Fibroblast factor receptor 1 4.34 growth factor receptor
API1 Apoptosis inhibitor 1 4.26 inhibition of apoptosis
ITGA8 Integrin alpha 8 3.95 cell and matrix adhesion
LAMB1 Laminin, beta1 3.88 extracellular matrix
FGF1 Fibroblast growth factor 1 3.79 growth factor
SDC1 Syndecan 1 3.19 membrane protein
CTNNB1 Catenin, beta1 3.03 cell adhesion