|
PCOS (n = 52)
|
Controls (n = 26)
|
---|
Age (years)
|
24.44 ± 5.49
|
25.96 ± 7.28
|
BMI (kg/m2)
|
28.79 ± 5.66
|
27.03 ± 6.04
|
WHR
|
0.85 ± 0.06
|
0.79 ± 0.06**
|
Total body FM (kg)
|
32.94 ± 11.58
|
28.79 ± 11.49
|
SBP (mm Hg)
|
108.46 ± 12.46
|
107.88 ± 12.66
|
DBP (mm Hg)
|
72.01 ± 9.96
|
70.38 ± 9.26
|
ucOC (ng/ml)
|
3.11 ± 0.68
|
2.79 ± 0.84#
|
OC (ng/ml)
|
13.76 ± 6.58
|
13.07 ± 6.55
|
β-CrossLaps (ng/ml)
|
0.539 ± 0.426
|
0.528 ± 0.334
|
TT (nmol/l)
|
3.04 ± 1.20
|
1.91 ± 0.80***
|
cFT (nmol/l)
|
0.051 ± 0.027
|
0.020 ± 0.012***
|
SHBG (nmol/l)
|
47.58 ± 32.09
|
88.03 ± 41.19***
|
Glucose (mg/dl)
|
85.57 ± 7.90
|
84.53 ± 7.03
|
Insulin (μU/ml)
|
16.56 ± 6.83
|
12.40 ± 3.81*
|
HOMA-IR
|
3.54 ± 1.64
|
2.60 ± 0.87**
|
QUICKI
|
0.322 ± 0.020
|
0.334 ± 0.017*
|
Hs-CRP (mg/l)
|
5.51 ± 3.91
|
4.04 ± 3.87
|
- Results are presented as mean ± SD and compared by Mann Whitney or two-tailed independent t-test, as appropriated. Abbreviations: BMI, body mass index, WHR, waist-to-hip ratio, FM, fat mass, SBP, systolic blood pressure, DBP, diastolic blood pressure, ucOC, under-carboxylated osteocalcin, OC, (1-43/49) osteocalcin, TT, total testosterone, cFT, calculated free testosterone, SHBG, sex hormone-binding globulin, HOMA-IR, homeostasis model assessment for insulin resistance, QUICKI, quantitative insulin sensitivity check index, Hs-CRP, high sensitivity C-reactive protein. *p < 0.05, **p < 0.01, ***p < 0.001, #p = 0.070 and p = 0.016 after adjusting for total body fat mass.