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Table 3 Multivariate analysis of prognostic factors for the overall patient cohort

From: Treatment reality in elderly patients with advanced ovarian cancer: a prospective analysis of the OVCAD consortium

 

Progression-free survival

Overall survival

 

HR

95% CI

p value

HR

95% CI

p value

FIGO stage IV vs. II-IIIC

2.169

1.489

3.159

<0.001

1.730

1.135

2.635

0.011

Grading

        

G2 vs. G1

1.809

0.711

4.604

0.213

1.681

0.560

5.049

0.355

G3 vs. G1

1.835

0.742

4.535

0.189

1.823

0.638

5.214

0.262

Lymph-node status

        

N1 vs. N0

1.046

0.732

1.494

0.805

1.495

0.913

2.448

0.110

Nx vs. N0

1.455

0.949

2.231

0.085

2.018

1.125

3.619

0.018

Residual tumor (yes vs. no)

1.384

0.995

1.926

0.054

1.568

1.038

2.369

0.033

Peritoneal carcinomatosis (yes vs. no)

2.600

1.811

3.733

<0.001

2.528

1.538

4.153

<0.001

Histologic subtype

        

Serous vs. mucinous

0.852

0.170

2.915

0.630

0.386

0.090

1.658

0.201

Serous vs. other

0.833

0.531

1.305

0.766

0.735

0.432

1.253

0.258

Age (<70y vs. ≥70y)

1.226

0.853

1.761

0.272

1.836

1.207

2.794

0.005

ECOG

        

≥1 vs. 0

1.137

0.824

1.571

0.434

1.315

0.842

2.052

0.229

Unknown vs. 0

0.852

0.409

1.775

0.669

1.185

0.457

3.070

0.727

  1. Detailed analysis of possible prognostic factors regarding their statistical significance and independence by cox regression model for the overall patient cohort (n = 275).
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Journal of Ovarian Research

ISSN: 1757-2215

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