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Table 3 Multivariate analysis of prognostic factors for the overall patient cohort

From: Treatment reality in elderly patients with advanced ovarian cancer: a prospective analysis of the OVCAD consortium

  Progression-free survival Overall survival
  HR 95% CI p value HR 95% CI p value
FIGO stage IV vs. II-IIIC 2.169 1.489 3.159 <0.001 1.730 1.135 2.635 0.011
Grading         
G2 vs. G1 1.809 0.711 4.604 0.213 1.681 0.560 5.049 0.355
G3 vs. G1 1.835 0.742 4.535 0.189 1.823 0.638 5.214 0.262
Lymph-node status         
N1 vs. N0 1.046 0.732 1.494 0.805 1.495 0.913 2.448 0.110
Nx vs. N0 1.455 0.949 2.231 0.085 2.018 1.125 3.619 0.018
Residual tumor (yes vs. no) 1.384 0.995 1.926 0.054 1.568 1.038 2.369 0.033
Peritoneal carcinomatosis (yes vs. no) 2.600 1.811 3.733 <0.001 2.528 1.538 4.153 <0.001
Histologic subtype         
Serous vs. mucinous 0.852 0.170 2.915 0.630 0.386 0.090 1.658 0.201
Serous vs. other 0.833 0.531 1.305 0.766 0.735 0.432 1.253 0.258
Age (<70y vs. ≥70y) 1.226 0.853 1.761 0.272 1.836 1.207 2.794 0.005
ECOG         
≥1 vs. 0 1.137 0.824 1.571 0.434 1.315 0.842 2.052 0.229
Unknown vs. 0 0.852 0.409 1.775 0.669 1.185 0.457 3.070 0.727
  1. Detailed analysis of possible prognostic factors regarding their statistical significance and independence by cox regression model for the overall patient cohort (n = 275).